Gunstensen J, Goldman B S, Scully H E, Huckell V F, Adelman A G
Ann Thorac Surg. 1976 Dec;22(6):535-45. doi: 10.1016/s0003-4975(10)64472-4.
Over a two-year period about 1,000 operations were performed with cardiopulmonary bypass. Intraaortic balloon pump assistance (IABP) was employed on 150 occasions, and a review of these has permitted clarification of the indications for its use. Sixty patients had IABP for carcinogenic shock either after infarction or cardiotomy, and 37 (62%) survived. Preoperative IABP in 90 high-risk patients resulted in survival for 79 (88%). The indications for prophylactic IABP included: (1) relief of severe pain, which occurred in 42 patients with acute coronary insufficiency, (2) improvement in the coronary perfusion pressure, which was accomplished in 20 patients with significant left main coronary artery occlusion or its equivalent, and (3) protection of left ventricular function, which war carried out in 28 patients with an LV ejection fraction of less than 0.40. The significance of the preoperative endocardial viability ratio (EVR) in relation to prophylactic IABP was also assessed: an EVR below 0.70 appears to be an indication for preoperative IABP.
在两年时间里,进行了约1000例体外循环手术。150例使用了主动脉内球囊反搏辅助(IABP),对这些病例的回顾有助于明确其使用指征。60例患者在心肌梗死或心脏切开术后因心源性休克使用IABP,37例(62%)存活。90例高危患者术前使用IABP,79例(88%)存活。预防性IABP的指征包括:(1)缓解严重疼痛,42例急性冠状动脉供血不足患者出现这种情况;(2)改善冠状动脉灌注压,20例左主干冠状动脉严重闭塞或等同情况的患者实现了这一点;(3)保护左心室功能,28例左心室射血分数低于0.40的患者进行了此项操作。还评估了术前心内膜活力比值(EVR)与预防性IABP的关系:EVR低于0.70似乎是术前IABP的一个指征。