荚膜甲基球菌中的δ8(14)-类固醇
Delta8(14)-steroids in the bacterium Methylococcus capsulatus.
作者信息
Bouvier P, Rohmer M, Benveniste P, Ourisson G
出版信息
Biochem J. 1976 Nov;159(2):267-71. doi: 10.1042/bj1590267.
Abstract
The 4,4-dimethyl and 4alpha-methyl sterols of the bacterium Methylococcus capsulatus were identified as 4,4-dimethyl- and 4alpha-methyl-5alpha-cholest-8(14)-en-3beta-ol and 4,4-dimethyl- and 4alpha-methyl-5alpha-cholesta-8(14),24-dien-3beta-ol. Sterol biosynthesis is blocked at the level of 4alpha-methyl delta8(14)-sterols.
摘要
荚膜甲基球菌的4,4-二甲基和4α-甲基甾醇被鉴定为4,4-二甲基-和4α-甲基-5α-胆甾-8(14)-烯-3β-醇以及4,4-二甲基-和4α-甲基-5α-胆甾-8(14),24-二烯-3β-醇。甾醇生物合成在4α-甲基δ8(14)-甾醇水平受阻。
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