• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

海盘车(Asterias rubens)的甾醇

The sterols of the echinoderm Asterias rubens.

作者信息

Smith A G, Rubinstein I, Goad L J

出版信息

Biochem J. 1973 Nov;135(3):443-55. doi: 10.1042/bj1350443.

DOI:10.1042/bj1350443
PMID:4772271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1165846/
Abstract
  1. Twenty-two sterols were identified in the starfish Asterias rubens (Phylum, Echinodermata; Class, Asteroidea). 2. The major 4-demethyl sterols had a Delta(7) bond and the C(27) compound 5alpha-cholest-7-en-3beta-ol predominated over other mono- and di-unsaturated sterols belonging to the C(26), C(27), C(28) and C(29) series. 3. Small amounts of cholest-5-en-3beta-ol and 5alpha-cholestan-3beta-ol were also present. 4. The minor sterols identified all contained either one or two methyl groups at C-4 and are considered to be potential biosynthetic precursors of 5alpha-cholest-7-en-3beta-ol. 5. Three sterols possessing a 9beta,19-cyclopropane ring were also isolated and were probably derived by the starfish from a dietary source.
摘要
  1. 在红海盘车(门,棘皮动物门;纲,海星纲)中鉴定出了22种甾醇。2. 主要的4-去甲基甾醇具有Δ⁷键,并且C₂₇化合物5α-胆甾-7-烯-3β-醇比属于C₂₆、C₂₇、C₂₈和C₂₉系列的其他单不饱和及双不饱和甾醇更为常见。3. 还存在少量的胆甾-5-烯-3β-醇和5α-胆甾烷-3β-醇。4. 鉴定出的次要甾醇在C-4位均含有一个或两个甲基,被认为是5α-胆甾-7-烯-3β-醇的潜在生物合成前体。5. 还分离出了三种具有9β,19-环丙烷环的甾醇,它们可能是海星从食物来源中获取的。

相似文献

1
The sterols of the echinoderm Asterias rubens.海盘车(Asterias rubens)的甾醇
Biochem J. 1973 Nov;135(3):443-55. doi: 10.1042/bj1350443.
2
Sterol biosynthesis in the echinoderm Asterias rubens.海胆纲动物红海盘车中的甾醇生物合成。
Biochem J. 1975 Jan;146(1):25-33. doi: 10.1042/bj1460025.
3
The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus.棘皮动物红海星和多棘海盘车将胆甾-5-烯-3β-醇转化为胆甾-7-烯-3β-醇的过程。
Biochem J. 1975 Jan;146(1):35-40. doi: 10.1042/bj1460035.
4
Chemical synthesis, spectral properties, and chromatography of 4alpha-methyl and 4beta-methyl isomers of (24R)-24-ethyl-5alpha-cholestan-3beta-ol and (24S)-24-ethyl-cholesta-5,22-dien-3beta-ol.(24R)-24-乙基-5α-胆甾烷-3β-醇和(24S)-24-乙基-胆甾-5,22-二烯-3β-醇的4α-甲基和4β-甲基异构体的化学合成、光谱性质及色谱分析
Steroids. 1975 Sep;26(3):339-57. doi: 10.1016/0039-128x(75)90079-3.
5
The sterols of echinoderms.棘皮动物的固醇类物质。
Proc R Soc Lond B Biol Sci. 1972 Feb 15;180(1059):223-46. doi: 10.1098/rspb.1972.0016.
6
Sterol biosynthesis in the starfish Asterias rubens and Henricia sanguinolenta.海星红斑海盘车和血红色亨氏海星中的甾醇生物合成。
Biochem J. 1971 Jul;123(4):671-3. doi: 10.1042/bj1230671.
7
The distribution of free sterols, polyhydroxysteroids and steroid glycosides in various body components of the starfish Patiria (=Asterina) pectinifera.海星多棘海盘车(= 海燕)各身体部位中游离甾醇、多羟基甾类化合物和甾类糖苷的分布情况。
Comp Biochem Physiol B Biochem Mol Biol. 2001 Jan;128(1):43-52. doi: 10.1016/s1096-4959(00)00317-1.
8
Effect of trans-1,4-bis(2-chlorobenzylaminomethyl) cyclohexane dihydrochloride and carbon monoxide on hepatic cholesterol biosynthesis from 4,4,-dimethyl sterols in vitro.反式-1,4-双(2-氯苄氨基甲基)环己烷二盐酸盐与一氧化碳对体外4,4'-二甲基甾醇肝胆固醇生物合成的影响
Biochim Biophys Acta. 1975 Feb 20;380(2):270-81. doi: 10.1016/0005-2760(75)90013-2.
9
Inhibition of sterol biosynthesis in L cells and mouse liver cells by 15-oxygenated sterols.15-氧化甾醇对L细胞和小鼠肝细胞中甾醇生物合成的抑制作用。
J Biol Chem. 1977 Dec 25;252(24):8975-80.
10
Mode of formulation of cholesta-5,7-dien-3beta-ol from Cholest-5-en-3beta-ol by Larvae of Calliphora erythrocephala.红头丽蝇幼虫将胆甾-5-烯-3β-醇转化为胆甾-5,7-二烯-3β-醇的方式。
Biochem J. 1975 Nov;152(2):303-11. doi: 10.1042/bj1520303.

引用本文的文献

1
Sterols and their biosynthesis in some freshwater bivalves.一些淡水双壳贝类中的甾醇及其生物合成
Lipids. 1981 Sep;16(9):663-9. doi: 10.1007/BF02535061.
2
Conformational analysis of 9beta,19-cyclopropyl sterols: Detection of the pseudoplanar conformer by nuclear Overhauser effects and its functional implications.9β,19-环丙基甾体的构象分析:通过核Overhauser 效应检测到拟平面构象及其功能意义。
Proc Natl Acad Sci U S A. 1988 Aug;85(16):5759-63. doi: 10.1073/pnas.85.16.5759.
3
The isolation of cholest-5-ene-3beta,26-diol from human brain.从人脑中分离出胆甾-5-烯-3β,26-二醇。
Biochem J. 1974 Jun;139(3):793-5. doi: 10.1042/bj1390793.
4
Sterol biosynthesis by the sea urchin Echinus esculentus.海胆(Echinus esculentus)的固醇生物合成。
Biochem J. 1974 Aug;142(2):421-7. doi: 10.1042/bj1420421.
5
Fate of dietary sterols in hydrogenated oils and fats.氢化油脂中膳食甾醇的去向
J Am Oil Chem Soc. 1975 Sep;52(9):345-8. doi: 10.1007/BF02639192.
6
The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus.棘皮动物红海星和多棘海盘车将胆甾-5-烯-3β-醇转化为胆甾-7-烯-3β-醇的过程。
Biochem J. 1975 Jan;146(1):35-40. doi: 10.1042/bj1460035.
7
Sterol biosynthesis in the echinoderm Asterias rubens.海胆纲动物红海盘车中的甾醇生物合成。
Biochem J. 1975 Jan;146(1):25-33. doi: 10.1042/bj1460025.
8
Delta8(14)-steroids in the bacterium Methylococcus capsulatus.荚膜甲基球菌中的δ8(14)-类固醇
Biochem J. 1976 Nov;159(2):267-71. doi: 10.1042/bj1590267.
9
Effects of miconazole and dodecylimidazole on sterol biosynthesis in Ustilago maydis.咪康唑和十二烷基咪唑对玉米黑粉菌中甾醇生物合成的影响。
Antimicrob Agents Chemother. 1979 Apr;15(4):603-7. doi: 10.1128/AAC.15.4.603.

本文引用的文献

1
Characterization of sterols by gas chromatography-mass spectrometry of the trimethylsilyl ethers.通过三甲基硅醚的气相色谱-质谱联用对甾醇进行表征。
Lipids. 1968 Sep;3(5):391-402. doi: 10.1007/BF02531277.
2
Skin sterols. I. Colorimetric determination of cholesterol and other sterols in skin.皮肤甾醇。I. 皮肤中胆固醇及其他甾醇的比色测定
J Biol Chem. 1952 Apr;195(2):615-21.
3
IDENTIFICATION AND QUANTIFICATION OF NEUTRAL FECAL STEROIDS BY GAS-LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRY: STUDIES OF HUMAN EXCRETION DURING TWO DIETARY REGIMENS.通过气液色谱法和质谱法鉴定和定量中性粪便类固醇:两种饮食方案下人体排泄的研究。
J Lipid Res. 1964 Apr;5:245-62.
4
FRACTIONATION OF CHOLESTEROL ESTERS BY THIN-LAYER CHROMATOGRAPHY.用薄层色谱法分离胆固醇酯
J Lipid Res. 1963 Jul;4:357-9.
5
[Studies on steroids. XXIX. Experiments on the synthesis of cholesta-7,22-dien-3beta-ol].[甾体化合物的研究。二十九。胆甾-7,22-二烯-3β-醇的合成实验]
Chem Pharm Bull (Tokyo). 1963 Apr;11:529-30. doi: 10.1248/cpb.11.529.
6
Marine sterols. 6. Sterol biosynthesis in molluscs and echinoderms.海洋甾醇。6. 软体动物和棘皮动物中的甾醇生物合成。
Can J Biochem Physiol. 1960 Sep;38:997-1002.
7
Studies on the constituents of rice bran oil. II. Structure of oryzanol-A.米糠油成分的研究。II. 谷维素A的结构。
Pharm Bull. 1957 Feb;5(1):40-4. doi: 10.1248/cpb1953.5.40.
8
The metabolism of cholesterol by the echinoderms Aterias rubens and Solaster papposus.棘皮动物红砂海星和多棘海盘车对胆固醇的代谢
FEBS Lett. 1971 Jan 25;12(4):233-235. doi: 10.1016/0014-5793(71)80028-5.
9
Studies on phytosterol biosynthesis: the sterols of Larix decidua leaves.植物甾醇生物合成的研究:欧洲落叶松树叶中的甾醇
Eur J Biochem. 1967 May;1(3):357-62. doi: 10.1007/978-3-662-25813-2_49.
10
Mass spectrometric investigations of some unsaturated sterols biosynthetically related to cholesterol.对一些与胆固醇有生物合成关联的不饱和甾醇的质谱研究。
Steroids. 1967 Sep;10(3):189-97. doi: 10.1016/0039-128x(67)90046-3.