多价离子引起的双层膜结构变化。

Structural changes in bilayer membranes by multivalent ions.

作者信息

Haller I, Freiser M J

出版信息

Biochim Biophys Acta. 1976 Dec 14;455(3):739-48. doi: 10.1016/0005-2736(76)90044-4.

Abstract

Formation of microlenses, a reduction in thickness, and a change in mechanical properties have been observed when Ca2+ or other multivalent ions are added to bathing solutions of Mueller-Rudin membranes of acidic phospholipids. The observations are interpreted as an extrusion of residual solvent from the hydrocarbon core of the bilayer due to changes in packing imposed by the reduction of electrostatic repulsion of the head groups.

摘要

当向酸性磷脂的穆勒 - 鲁丁膜的浴液中添加Ca2+或其他多价离子时，已观察到微透镜的形成、厚度的减小以及机械性能的变化。这些观察结果被解释为由于头部基团静电排斥减少所导致的堆积变化，使得双层烃核中的残余溶剂被挤出。