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骨佩吉特病和原发性甲状旁腺功能亢进症中尿羟赖氨酸糖苷的来源。

The origin of urinary hydroxylysyl glycosides in Paget's disease of bone and in primary hyperparathyroidism.

作者信息

Askenasi R, De Backer M, Devos A

出版信息

Calcif Tissue Res. 1976 Nov 24;22(1):35-40. doi: 10.1007/BF02010344.

Abstract

The urinary excretion of glucosyl-galactosyl-hydroxylysine and of galactosyl-hydroxylysine were studied in Paget's disease of bone and in primary hyperparathyroidism. Both metabolites were increased in these diseases. Although glucosyl-galactosyl-hydroxylysine is not abundant in bone collagen, it is possible that a part of it originates from calcified tissue.

摘要

对骨Paget病和原发性甲状旁腺功能亢进症患者的葡萄糖基 - 半乳糖基 - 羟赖氨酸及半乳糖基 - 羟赖氨酸的尿排泄情况进行了研究。在这些疾病中,这两种代谢产物均有所增加。尽管葡萄糖基 - 半乳糖基 - 羟赖氨酸在骨胶原中含量并不丰富,但它有可能部分来源于钙化组织。

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