乳糜泻与疱疹样皮炎：二者关系的进一步研究
Coeliac disease and dermatitis herpetiformis: further studies of their relationship.
作者信息
Scott B B, Young S, Rajah S M, Marks J, Losowsky M S
出版信息
Gut. 1976 Oct;17(10):759-62. doi: 10.1136/gut.17.10.759.
Abstract
Using diagnostic criteria which are currently accepted as most reliable we have found that 19% (9/47) of patients with dermatitis herpetiformis (DH) have no evidence of coeliac disease. The incidence of HL-A8 in the DH patients was 78%, which is considerably greater than that in healthy controls and no different from that reported in coeliac disease. Furthermore, the incidence of HL-A8 was just as much increased in those DH patients without evidence of coeliac disease suggesting that HL-A8 is associated with DH per se--that is, regardless of its association with coeliac disease.
摘要
采用目前被认为最可靠的诊断标准，我们发现疱疹样皮炎（DH）患者中有19%（9/47）没有乳糜泻的证据。DH患者中HL - A8的发生率为78%，这显著高于健康对照组，且与乳糜泻报告的发生率无差异。此外，在那些没有乳糜泻证据的DH患者中，HL - A8的发生率同样升高，这表明HL - A8与DH本身相关——也就是说，无论其与乳糜泻的关联如何。
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