Stokes P L, Asquith P, Holmes G K, MacKintosh P, Cooke W T
Gut. 1973 Aug;14(8):627-30. doi: 10.1136/gut.14.8.627.
In a study of histocompatibility antigens in adult coeliac disease the HL-A phenotypes have been determined in 117 patients and 149 of their first-degree relatives, of whom 94 had had a jejunal biopsy performed. There was an increased frequency of the HL-A 8 antigen in the patients and their relatives. Family studies showed no irregularity in the inheritance of both this antigen and the HL-A 1 and 8 haplotype.
在一项关于成人乳糜泻组织相容性抗原的研究中,已对117例患者及其149名一级亲属的HL - A表型进行了测定,其中94人已接受空肠活检。患者及其亲属中HL - A8抗原的频率增加。家系研究表明,该抗原以及HL - A1和8单倍型的遗传均无异常。