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喂食含或不含低剂量静脉注射地西泮的高纤维饮食的猫中不透射线标志物的胃排空和肠道转运时间

Gastric emptying and intestinal transit times of radiopaque markers in cats fed a high-fiber diet with and without low-dose intravenous diazepam.

作者信息

Chandler M L, Guilford W G, Lawoko C R, Whittem T

机构信息

The Department of Veterinary Clinical Sciences, Massey University, Palmerston North, New Zealand.

出版信息

Vet Radiol Ultrasound. 1999 Jan-Feb;40(1):3-8. doi: 10.1111/j.1740-8261.1999.tb01831.x.

DOI:10.1111/j.1740-8261.1999.tb01831.x
PMID:10023988
Abstract

Reference ranges for gastric emptying time (GET), small intestinal transit time (SITT), and colonic transit time of 1.5-mm and 5-mm radiopaque markers in healthy cats fed a high-fiber meal were determined, and the influence of low-dose diazepam intravenous injection on the gastrointestinal transit of the markers was examined. The mean GETs and SITTs, and the mean residence times (MRTs) and geometric centers (GCs) of markers in the colon were determined. The effect of intravenous diazepam injection and marker size on these parameters was examined. Diazepam injection had no significant influence on gastrointestinal transit. The GETs of the 1.5-mm markers were significantly more rapid than those of the 5.0-mm markers. There were no significant differences between the SITTs or GCs of the 1.5-mm and 5.0-mm markers. Reference values were developed for GET, SITT, and colonic transit of radiopaque markers for cats fed a high-fiber meal. Diazepam injection had no effect on these parameters.

摘要

测定了喂食高纤维日粮的健康猫的胃排空时间(GET)、小肠转运时间(SITT)以及1.5毫米和5毫米不透射线标志物的结肠转运时间的参考范围,并研究了静脉注射低剂量地西泮对标志物胃肠道转运的影响。测定了平均GET和SITT,以及结肠中标志物的平均驻留时间(MRT)和几何中心(GC)。研究了静脉注射地西泮和标志物大小对这些参数的影响。注射地西泮对胃肠道转运没有显著影响。1.5毫米标志物的GET明显快于5.0毫米标志物。1.5毫米和5.0毫米标志物的SITT或GC之间没有显著差异。建立了喂食高纤维日粮的猫的GET、SITT和不透射线标志物结肠转运的参考值。注射地西泮对这些参数没有影响。

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