Melton L J, Amadio P C, Crowson C S, O'Fallon W M
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.
Osteoporos Int. 1998;8(4):341-8. doi: 10.1007/s001980050073.
In this population-based descriptive study covering the 50-year period, 1945-94, there was a statistically significant increase in distal forearm fractures due to severe trauma in both women and men (p < 0.001) but no secular increase in fractures due to moderate trauma (approximately osteoporosis). Since fractures attributed to severe trauma comprised a greater proportion of the total in men (52%) than women (21%), an overall doubling of age-adjusted forearm fracture incidence in men between 1945 and 1994 was statistically significant (p < 0.001), but the 7% increase in age-adjusted rates among women was not (p = 0.90). While the epidemiological pattern of distal forearm fracture incidence in Rochester was similar to that seen elsewhere, the overall incidence rate of 287.4 per 100,000 person-years (95% CI 267.7-307.1) in 1985-94 was less than current rates in Sweden, presumably because the great increase in distal forearm fracture incidence seen, for example, in Malmö between 1953-57 and 1980-81 was not observed in Rochester. The trends in distal forearm fracture rates in Rochester men and women over the past 50 years are broadly consistent with trends in hip fracture incidence in this community over the same time span.
在这项涵盖1945年至1994年这50年期间的基于人群的描述性研究中，因严重创伤导致的前臂远端骨折在男性和女性中均有统计学意义的显著增加（p < 0.001），但因中度创伤（近似骨质疏松）导致的骨折无长期增加趋势。由于因严重创伤导致的骨折在男性骨折总数中所占比例（52%）高于女性（21%），1945年至1994年间男性年龄调整后的前臂骨折发病率总体翻倍具有统计学意义（p < 0.001），但女性年龄调整后的发病率增加7%则无统计学意义（p = 0.90）。虽然罗切斯特前臂远端骨折发病率的流行病学模式与其他地方相似，但1985年至1994年期间每10万人年287.4例（95%可信区间267.7 - 307.1）的总体发病率低于瑞典目前的发病率，推测是因为例如在马尔默1953 - 57年至1980 - 81年期间观察到的前臂远端骨折发病率大幅增加在罗切斯特未出现。过去50年罗切斯特男性和女性前臂远端骨折率的趋势与该社区同期髋部骨折发病率的趋势大致一致。
