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天生的运动能力与心血管疾病易感性。

Natural sporting ability and predisposition to cardiovascular disorders.

作者信息

Lean M E, Han T S

机构信息

University Department of Human Nutrition, Glasgow Royal Infirmary, UK.

出版信息

QJM. 1998 Sep;91(9):641-6. doi: 10.1093/qjmed/91.9.641.

Abstract

We tested the hypothesis that people with a natural ability in 'power sports' (a presumed marker for predominance of type 2, glycolytic muscle fibres) might have increased risks of coronary heart disease (CHD) compared to those with a natural ability in 'endurance sports' (as a marker for predominance of type 1, oxidative muscle fibres). We examined subsequent cardiovascular disorders retrospectively in 231 male former soldiers, aged 34-87 years, who had undergone a course in physical training in the Army School of Physical Training, Aldershot, UK, who assessed themselves as having natural ability in either power (n = 107) or endurance (n = 124) sports. The proportion with CHD, defined as angina and/or coronary angioplasty and/or coronary artery bypass graft and/or heart attack was 18.7% in the 'power group' vs. 9.7% in the 'endurance group' (difference: chi 2 = 3.9, p = 0.05). The proportions with CHD and/or risk factors rose to 39.3% in the 'power group' vs. 25.8% in the 'endurance group' (difference: chi 2 = 4.8, p = 0.03). Under logistic regression analysis, compared to the 'endurance group', the 'power group' had 2.2 (95% CI: 1.00-4.63) the risk of developing CHD, and 1.86 (95% confidence interval: 1.06 to 3.25) the risk of developing CHD and/or risk factors. Men with a natural ability in 'power sports' are at increased risk of developing cardiovascular disorders, compared to men with a natural ability in 'endurance sports'. A predominance of type 2, glycolytic muscle fibres, presumably of genetic origin, may predispose to cardiovascular disorders.

摘要

我们检验了这样一个假设

与那些在“耐力运动”方面有天赋(作为1型氧化肌纤维占优势的标志)的人相比,在“力量运动”方面有天赋(作为2型糖酵解肌纤维占优势的假定标志)的人患冠心病(CHD)的风险可能更高。我们对231名年龄在34 - 87岁的男性退伍军人进行了回顾性研究,这些人曾在英国奥尔德肖特的陆军体育训练学校接受过体育训练课程,他们自我评估在力量运动(n = 107)或耐力运动(n = 124)方面有天赋。“力量组”中被定义为心绞痛和/或冠状动脉血管成形术和/或冠状动脉搭桥术和/或心脏病发作的冠心病患者比例为18.7%,而“耐力组”为9.7%(差异:卡方 = 3.9,p = 0.05)。“力量组”中患冠心病和/或有风险因素的比例升至39.3%,而“耐力组”为25.8%(差异:卡方 = 4.8,p = 0.03)。在逻辑回归分析中,与“耐力组”相比,“力量组”患冠心病的风险是其2.2倍(95%置信区间:1.00 - 4.63),患冠心病和/或有风险因素的风险是其1.86倍(95%置信区间:1.06至3.25)。与在“耐力运动”方面有天赋的男性相比,在“力量运动”方面有天赋的男性患心血管疾病的风险更高。推测起源于遗传的2型糖酵解肌纤维占优势可能易患心血管疾病。

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