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联合手术、放射治疗和非甾体抗炎药治疗脊髓损伤中的未成熟异位骨化

The treatment of immature heterotopic ossification in spinal cord injury with combination surgery, radiation therapy and NSAID.

作者信息

Freebourn T M, Barber D B, Able A C

机构信息

Spinal Cord Injury Center, South Texas Veterans Health Care System and Department of Rehabilitation Medicine, The University of Texas Health Science Center at San Antonio, USA.

出版信息

Spinal Cord. 1999 Jan;37(1):50-3. doi: 10.1038/sj.sc.3100719.

DOI:10.1038/sj.sc.3100719
PMID:10025696
Abstract

Heterotopic ossification (HO) is a frequent complication associated with spinal cord injury. Management of HO consists of a combination of range-of-motion, diphosphonates, nonsteroidal antiinflammatory agents, radiation therapy, and in some cases, surgical resection. The appropriate timing of surgical resection has traditionally been based on maturity of the HO. The case presented is that of a 33-year-old male with T8 complete paraplegia who developed HO about the left hip resulting in impaired sitting. The patient underwent successful surgical wedge resection of the HO despite apparent immaturity of the HO. A comprehensive review of the literature is presented which suggests that early resection of immature HO may not be predictive of a higher recurrence rate.

摘要

异位骨化(HO)是脊髓损伤常见的并发症。HO的治疗包括活动度训练、双膦酸盐、非甾体抗炎药、放射治疗,在某些情况下还包括手术切除。传统上,手术切除的合适时机基于HO的成熟度。本文报道了一名33岁男性,T8完全性截瘫,左髋部发生HO导致坐位障碍。尽管HO明显未成熟,该患者仍成功接受了HO的楔形手术切除。本文对文献进行了全面综述,提示早期切除未成熟的HO可能不会导致更高的复发率。

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