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一项基于大规模人群的研究中教育与痴呆症发病率:鹿特丹研究

Education and the incidence of dementia in a large population-based study: the Rotterdam Study.

作者信息

Ott A, van Rossum C T, van Harskamp F, van de Mheen H, Hofman A, Breteler M M

机构信息

Department of Epidemiology & Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.

出版信息

Neurology. 1999 Feb;52(3):663-6. doi: 10.1212/wnl.52.3.663.

DOI:10.1212/wnl.52.3.663
PMID:10025813
Abstract

We assessed the risk of dementia by educational level in a prospective population-based study. In the Rotterdam Study, 6,827 nondemented participants with known education level were followed for an average of 2.1 years. During this period, 137 new cases of dementia occurred. Low education was associated with higher dementia risk in women but not in men, suggesting that the association is modified by sex. Our data indicate that cross-sectional studies may overrate the association between education and risk of dementia.

摘要

在一项基于人群的前瞻性研究中,我们按教育水平评估了患痴呆症的风险。在鹿特丹研究中,对6827名已知教育水平的非痴呆参与者进行了平均2.1年的随访。在此期间,出现了137例新的痴呆症病例。低教育水平与女性较高的痴呆症风险相关,但与男性无关,这表明这种关联会因性别而有所不同。我们的数据表明,横断面研究可能高估了教育与痴呆症风险之间的关联。

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