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通过超声心动图在清醒犬身上无创测量心室尺寸。

Ventricular dimensions measured noninvasively by echocardiography in the awake dog.

作者信息

Mashiro I, Nelson R R, Cohn J N, Franciosa J A

出版信息

J Appl Physiol. 1976 Dec;41(6):953-9. doi: 10.1152/jappl.1976.41.6.953.

Abstract

A surface echocardiographic technique was employed in 37 mongrel dogs for measurement of left ventricular dimensions. Intracardiac bolus injections of dextran were used as an echo contrast material to visualize cardiac chambers, and the identification of intracardiac structures was further confirmed by postmortem examination. The left ventricle could be satisfactorily visualized from both the right and left chest, providing two transverse left ventricular diameters nearly perpendicular to each other. End-diastolic and end-systolic diameter measurements in the two separate transverse planes differed by an average of only 0.07 and 0.1 cm, respectively, and dimensional measurements were reproducible from day to day. Diastolic diameter ranged from 3.0 to 4.7 cm (mean 3.7 cm) and systolic diameter 1.9 to 3.3 cm (mean 2.6 cm). Diameter was directly related to animal weight. Stroke volume calculated from the dimension measurements correlated with stroke volume calculated from indicator-dilution curves in 16 dogs. Ejection fraction averaged 0.67 and 0.54, depending on the formula used to calculate volumes. These results indicate that surface echocardiography can be employed to evaluate left ventricular dimensions in the awake dog.

摘要

采用表面超声心动图技术对37只杂种犬进行左心室尺寸测量。心内注射葡聚糖作为超声造影剂以显示心腔,心内结构的识别通过尸检进一步证实。从右胸和左胸均可满意地显示左心室,可获得两个近乎相互垂直的左心室横径。在两个独立横切面中测量的舒张末期和收缩末期直径,其差异平均分别仅为0.07 cm和0.1 cm,且尺寸测量具有每日重复性。舒张期直径范围为3.0至4.7 cm(平均3.7 cm),收缩期直径为1.9至3.3 cm(平均2.6 cm)。直径与动物体重直接相关。根据尺寸测量计算的每搏量与16只犬中通过指示剂稀释曲线计算的每搏量相关。射血分数平均为0.67和0.54,具体取决于用于计算容积的公式。这些结果表明,表面超声心动图可用于评估清醒犬的左心室尺寸。

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