Hartert T V, Wheeler A P, Sheller J R
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2650, USA.
Chest. 1999 Feb;115(2):475-81. doi: 10.1378/chest.115.2.475.
The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in obstructive airway disease.
Cross-sectional survey.
The ICU in a tertiary care academic hospital.
Twenty-six patients consecutively admitted to the ICU with obstructive airway disease, either asthma or COPD.
Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p < 0.0001). An analysis of the respiratory variations in the pulse oximetry waveforms in obstructive lung disease patients reflects the presence and degree of auto-positive end-expiratory pressure (auto-PEEP; p < 0.0001).
We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in obstructive airway disease patients.
本横断面研究的目的是证实脉搏血氧饱和度描记与奇脉相关这一观察结果,因此它是阻塞性气道疾病中气体潴留严重程度的一种衡量指标。
横断面调查。
一家三级医疗学术医院的重症监护病房。
26例因阻塞性气道疾病(哮喘或慢性阻塞性肺疾病)连续入住重症监护病房的患者。
46%的研究患者需要机械通气,69%的患者奇脉升高。我们将脉搏血氧饱和度基线描记的改变定义为呼吸波形变化(RWV)。RWV以数值形式测量,即相对于基线的毫米变化量。奇脉与脉搏血氧饱和度描记的RWV显著相关(p < 0.0001)。对阻塞性肺病患者脉搏血氧饱和度波形中的呼吸变化进行分析,反映了内源性呼气末正压(auto-PEEP)的存在及其程度(p < 0.0001)。
我们描述了在存在奇脉和auto-PEEP时脉搏血氧饱和度描记的特征性改变。由于重症监护病房和急诊科普遍都有脉搏血氧饱和度监测设备,它可能是一种有用的无创方法,可用于持续评估阻塞性气道疾病患者的奇脉和气体潴留严重程度。