Lipshitz H, Etheredge R, Glimcher M J
J Bone Joint Surg Am. 1976 Dec;58(8):1149-53.
The hexasamine content and swelling ratio of adult bovine articular cartilage were determined as functions of depth. Progressing from the surface downward, the hexosamine content increased rapidly to a depth equivalent to approximately 30 to 35 per cent of the total thickness of the uncalcified portion of the tissue, and thereafter decreased at a less rapid rate. The swelling ratio was relatively constant throughtout the first quarter of the tissue but diminished thereafter. At depths below 35 per cent, the curve for the decrease in swelling ratio with depth was similar in form to that for the decrease in hexosamine content. Considering the factors that determine the swelling ratio of polyelectrolyte gels, it is proposed that progressing down from the surface, the interaction between the macromolecular components of the tissue is increased to a depth equivalent to about one-third of the total thickness of the cartilage.
测定了成年牛关节软骨中六胺含量和肿胀率随深度的变化情况。从表面向下，六胺含量迅速增加，直至达到相当于组织未钙化部分总厚度约30%至35%的深度，此后下降速度变缓。在组织的前四分之一深度范围内，肿胀率相对恒定，但此后逐渐减小。在深度超过35%时，肿胀率随深度降低的曲线形态与六胺含量降低的曲线相似。考虑到决定聚电解质凝胶肿胀率的因素，有人提出，从表面向下，组织大分子成分之间的相互作用在达到软骨总厚度约三分之一的深度时会增强。
