Osborne C A, Sanderson S L, Lulich J P, Bartges J W, Ulrich L K, Koehler L A, Bird K A, Swanson L L
Minnesota Urolith Center, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, USA.
Vet Clin North Am Small Anim Pract. 1999 Jan;29(1):193-211, xiii. doi: 10.1016/s0195-5616(99)50011-9.
Cystine uroliths are a sequela to cystinuria, an inherited renal tubular defect in reabsorption of cystine and some other amino acids. At the Minnesota Urolith Center, 67 breeds of dogs were identified, including English Bulldogs, Dachshunds, Mastiffs, and Newfoundlands. In some dogs, the severity of cystinuria may decline with advancing age. Current recommendations for dissolution of cystine uroliths include various combinations of diet modification, diuresis administration of 2-MPG, and alkalinization of urine.
胱氨酸尿石症是胱氨酸尿症的后遗症，胱氨酸尿症是一种遗传性肾小管缺陷，会影响胱氨酸和其他一些氨基酸的重吸收。在明尼苏达尿石症中心，已鉴定出67个犬种，包括英国斗牛犬、腊肠犬、獒犬和纽芬兰犬。在一些犬中，胱氨酸尿症的严重程度可能会随着年龄的增长而减轻。目前关于溶解胱氨酸尿石症的建议包括饮食调整、给予2-巯基丙氨酸进行利尿以及碱化尿液等多种组合。
