Santo R M, Bechara S J, Kara-José N
Department of Ophthalmology, University of São Paulo, School of Medicine, Brazil.
Am J Ophthalmol. 1999 Feb;127(2):205-7. doi: 10.1016/s0002-9394(98)00349-3.
To report corneal topographic patterns in asymptomatic family members of a patient with pellucid marginal degeneration.
Computer-assisted corneal topography was used to study the corneas of five family members of a patient with pellucid marginal degeneration.
In all five asymptomatic family members, corneal biomicroscopy was normal. Corneal topography, however, showed various abnormalities in different members of this family, particularly a topographic pattern suggesting keratoconus in one family member and a topographic pattern suggesting pellucid marginal degeneration in another family member.
This study reinforces the hypothesis that corneal ectatic disorders may represent different manifestations of a clinical spectrum.
报告透明边缘变性患者无症状家庭成员的角膜地形图特征。
采用计算机辅助角膜地形图技术对一名透明边缘变性患者的五名家庭成员的角膜进行研究。
所有五名无症状家庭成员的角膜生物显微镜检查均正常。然而，角膜地形图显示该家族不同成员存在各种异常，特别是一名家庭成员的地形图表现提示圆锥角膜，另一名家庭成员的地形图表现提示透明边缘变性。
本研究强化了角膜扩张性疾病可能代表临床谱系不同表现的假说。
