LV Prasad Eye Institute, Hyderabad, India.
Cornea and Anterior Segment, LV Prasad Eye Institute, Hyderabad, India
BMJ Case Rep. 2022 Aug 19;15(8):e248599. doi: 10.1136/bcr-2021-248599.
A teenage boy presented to the clinic complaining of poor vision in both eyes. His best-corrected visual acuity was 20/25. The slit lamp examination revealed vertically oval corneas, crescentic peripheral inferior corneal thinning and ectasia in both eyes. Corneal topography showed against-the-rule astigmatism with mean keratometry (Km) of 45.1 and 45.2 dioptres in the right and left eyes, respectively. High-resolution optical coherence tomography corroborated the clinical findings, and the patient was diagnosed with pellucid marginal corneal degeneration (PMD). Collagen cross-linking was performed in the right eye. Left eye cross-linking is awaited. Although PMD is typically seen in middle-aged (third-fourth decade) patients, it can also occur at earlier ages. Collagen cross-linking can be considered to prevent the progression of the condition.
一位十几岁的男孩因双眼视力不佳到诊所就诊。他的最佳矫正视力为 20/25。裂隙灯检查显示双眼垂直椭圆形角膜、新月形周边下方角膜变薄和扩张。角膜地形图显示逆规散光，右眼和左眼平均角膜曲率（Km）分别为 45.1 和 45.2 屈光度。高分辨率光相干断层扫描证实了临床发现，该患者被诊断为边缘性角膜变性（PMD）。右眼行胶原交联治疗，左眼等待交联治疗。虽然 PMD 通常发生在中年（第三或第四十年）患者中，但也可发生在较年轻的年龄。胶原交联可被视为预防病情进展的一种手段。
