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法国儿童散发性肠炎沙门氏菌肠炎血清型感染发生的危险因素:一项全国性病例对照研究。

Risk factors for the occurrence of sporadic Salmonella enterica serotype enteritidis infections in children in France: a national case-control study.

作者信息

Delarocque-Astagneau E, Desenclos J C, Bouvet P, Grimont P A

机构信息

Réseau National de Santé Publique, Saint-Maurice, France.

出版信息

Epidemiol Infect. 1998 Dec;121(3):561-7. doi: 10.1017/s0950268898001460.

Abstract

To determine risk factors associated with the occurrence of sporadic cases of Salmonella enteritidis infections among children in France, we conducted a matched case-control study. Cases were identified between 1 March and 30 September 1995. One hundred and five pairs of cases and controls matched for age and place of residence were interviewed. In the 1-5 years age group, illness was associated with the consumption of raw eggs or undercooked egg-containing foods (OR 2.4, 95% CI 1.2-4.8). Storing eggs more than 2 weeks after purchase was associated with Salmonella enteritidis infection (OR 3.8, 95% CI 1.4-10.2), particularly during the summer period (OR 6.0, 95% CI 1.3-26.8). Cases were more likely to report a case of diarrhoea in the household 10-3 days before the onset of symptoms, particularly in the age group < or = 1 year (P = 0.01). This study confirms the link between eggs and the occurrence of sporadic cases of Salmonella enteritidis among children, highlights the potential role of prolonged egg storage and underlines the role of person-to-person transmission in infants.

摘要

为确定法国儿童散发性肠炎沙门氏菌感染病例发生的相关危险因素,我们开展了一项配对病例对照研究。病例于1995年3月1日至9月30日期间确定。对105对按年龄和居住地匹配的病例与对照进行了访谈。在1至5岁年龄组中,发病与食用生鸡蛋或未煮熟的含蛋食品有关(比值比2.4,95%可信区间1.2至4.8)。购买鸡蛋后储存超过2周与肠炎沙门氏菌感染有关(比值比3.8,95%可信区间1.4至10.2),尤其是在夏季(比值比6.0,95%可信区间1.3至26.8)。病例更有可能报告在症状出现前10至3天家庭中有腹泻病例,尤其是在年龄小于或等于1岁的年龄组(P = 0.01)。本研究证实了鸡蛋与儿童散发性肠炎沙门氏菌病例发生之间的联系,突出了鸡蛋长期储存的潜在作用,并强调了人际传播在婴儿中的作用。

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