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麻痹性痴呆中的人类白细胞抗原(HLA)抗原频率。

HLA antigen frequencies in paralytic dementia.

作者信息

Whitsett C, Turner W J, Lee T D, Dupont B

出版信息

J Neurol Sci. 1976 Dec;30(2-3):417-20. doi: 10.1016/0022-510x(76)90145-3.

Abstract

HLA typing was performed on 75 caucasian and 58 black patients with paralytic dementia hospitalized at 2 state mental institutions in New York. Serological testing was performed to confirm previous infection with T. pallidum. The caucasian patients showed an increase in B18(18.7% vs. 9.6% in controls). The black patients showed an increase in A2 (48.3% vs. 28.7% in controls) and an increase in B7 (27.6% vs. 15.7% in controls.

摘要

对在纽约2家国立精神病院住院的75名白种人和58名患有麻痹性痴呆的黑人患者进行了HLA分型。进行血清学检测以确认既往梅毒螺旋体感染情况。白种人患者中B18出现增加(18.7%,而对照组为9.6%)。黑人患者中A2出现增加(48.3%,而对照组为28.7%),B7也出现增加(27.6%,而对照组为15.7%)。

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