Cruikshank D P, Kaminsky D B, Ekbladh L E
J Reprod Med. 1976 Dec;17(6):327-30.
Colposcopic examination and directed biopsies were performed on 70 patients with abnormal cerivcal cytology. The correlation of the histology of the directed biopsies with the colposcopic appearance was 80%; it was 86% with the original Papanicolaou smear. In no case was the histology of a subsequent cone biopsy or hysterectomy specimen more advanced than that of the directed biopsy. Conization was avoided in 52 of the 70 patients and could have been avoided in seven others.
对70例宫颈细胞学异常的患者进行了阴道镜检查和定向活检。定向活检的组织学与阴道镜表现的相关性为80%;与最初的巴氏涂片的相关性为86%。在任何情况下,后续锥形活检或子宫切除标本的组织学都没有比定向活检更严重。70例患者中有52例避免了锥形切除术,另外7例本也可以避免。