金黄色葡萄球菌的表面蛋白黏附素
Surface protein adhesins of Staphylococcus aureus.
作者信息
Foster T J, Höök M
机构信息
Microbiology Dept, Moyne Institute of Preventive Medicine, Trinity College, Dublin, Ireland.
出版信息
Trends Microbiol. 1998 Dec;6(12):484-8. doi: 10.1016/s0966-842x(98)01400-0.
Abstract
Staphylococcus aureus can colonize the host to initiate infection by adhering to components of the extracellular matrix. Adherence is mediated by surface protein adhesins (MSCRAMMs). Ligand binding by these fibronectin-, fibrinogen- and collagen-binding proteins occurs by distinct mechanisms that are being investigated at the molecular level.
摘要
金黄色葡萄球菌可通过黏附于细胞外基质成分在宿主体内定殖以引发感染。黏附由表面蛋白黏附素（微生物表面成分识别黏附分子）介导。这些结合纤连蛋白、纤维蛋白原和胶原蛋白的蛋白与配体的结合通过不同机制发生，目前正在分子水平上对此进行研究。
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