• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

金黄色葡萄球菌的表面蛋白黏附素

Surface protein adhesins of Staphylococcus aureus.

作者信息

Foster T J, Höök M

机构信息

Microbiology Dept, Moyne Institute of Preventive Medicine, Trinity College, Dublin, Ireland.

出版信息

Trends Microbiol. 1998 Dec;6(12):484-8. doi: 10.1016/s0966-842x(98)01400-0.

DOI:10.1016/s0966-842x(98)01400-0
PMID:10036727
Abstract

Staphylococcus aureus can colonize the host to initiate infection by adhering to components of the extracellular matrix. Adherence is mediated by surface protein adhesins (MSCRAMMs). Ligand binding by these fibronectin-, fibrinogen- and collagen-binding proteins occurs by distinct mechanisms that are being investigated at the molecular level.

摘要

金黄色葡萄球菌可通过黏附于细胞外基质成分在宿主体内定殖以引发感染。黏附由表面蛋白黏附素(微生物表面成分识别黏附分子)介导。这些结合纤连蛋白、纤维蛋白原和胶原蛋白的蛋白与配体的结合通过不同机制发生,目前正在分子水平上对此进行研究。

相似文献

1
Surface protein adhesins of Staphylococcus aureus.金黄色葡萄球菌的表面蛋白黏附素
Trends Microbiol. 1998 Dec;6(12):484-8. doi: 10.1016/s0966-842x(98)01400-0.
2
Structural and functional role of Staphylococcus aureus surface components recognizing adhesive matrix molecules of the host.金黄色葡萄球菌表面成分识别宿主黏附基质分子的结构和功能作用。
Future Microbiol. 2009 Dec;4(10):1337-52. doi: 10.2217/fmb.09.102.
3
Matrix-binding proteins of Staphylococcus aureus: functional analysis of mutant and hybrid molecules.金黄色葡萄球菌的基质结合蛋白:突变体和杂交分子的功能分析
Microbiology (Reading). 1999 Sep;145 ( Pt 9):2497-2505. doi: 10.1099/00221287-145-9-2497.
4
The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus is a bifunctional protein that also binds to fibrinogen.金黄色葡萄球菌的纤连蛋白结合MSCRAMM FnbpA是一种双功能蛋白,它也能与纤维蛋白原结合。
J Biol Chem. 2000 May 5;275(18):13863-71. doi: 10.1074/jbc.275.18.13863.
5
Cellular invasion by Staphylococcus aureus involves a fibronectin bridge between the bacterial fibronectin-binding MSCRAMMs and host cell beta1 integrins.金黄色葡萄球菌的细胞侵袭涉及细菌纤连蛋白结合MSCRAMMs与宿主细胞β1整合素之间的纤连蛋白桥。
Eur J Cell Biol. 2000 Oct;79(10):672-9. doi: 10.1078/0171-9335-00104.
6
Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells.金黄色葡萄球菌的纤连蛋白结合蛋白A具有多个相互替代的结合区域,这些区域介导对纤连蛋白的粘附以及对内皮细胞的侵袭。
Cell Microbiol. 2001 Dec;3(12):839-51. doi: 10.1046/j.1462-5822.2001.00157.x.
7
Staphylococcus aureus fibronectin binding proteins A and B possess a second fibronectin binding region that may have biological relevance to bone tissues.金黄色葡萄球菌纤连蛋白结合蛋白A和B拥有第二个纤连蛋白结合区域,该区域可能与骨组织具有生物学相关性。
Calcif Tissue Int. 2002 May;70(5):416-21. doi: 10.1007/s00223-001-2073-z. Epub 2002 Mar 27.
8
Expression of the biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process.生物膜相关蛋白的表达会干扰金黄色葡萄球菌的宿主蛋白受体,并改变感染过程。
Infect Immun. 2002 Jun;70(6):3180-6. doi: 10.1128/IAI.70.6.3180-3186.2002.
9
Functional blocking of Staphylococcus aureus adhesins following growth in ex vivo media.在体外培养基中生长后金黄色葡萄球菌黏附素的功能阻断
Infect Immun. 2002 Oct;70(10):5339-45. doi: 10.1128/IAI.70.10.5339-5345.2002.
10
Role of fibronectin-binding MSCRAMMs in bacterial adherence and entry into mammalian cells.纤连蛋白结合性微生物表面成分识别黏附分子在细菌黏附和进入哺乳动物细胞中的作用。
Matrix Biol. 1999 Jun;18(3):211-23. doi: 10.1016/s0945-053x(99)00025-6.

引用本文的文献

1
Study on the Prevalence of Methicillin-Resistant Infection, Antibiotic Resistance Pattern, Biofilms Genes, and Antibiotic Resistance Genes from Clinical Samples.临床样本中耐甲氧西林感染的患病率、抗生素耐药模式、生物膜基因和抗生素耐药基因的研究。
Arch Razi Inst. 2024 Oct 31;79(5):923-928. doi: 10.32592/ARI.2024.79.5.923. eCollection 2024 Oct.
2
Advancing treatment strategies against MRSA: unveiling the potency of tubuloside A in targeting sortase A and mitigating pathogenicity.对抗耐甲氧西林金黄色葡萄球菌(MRSA)的治疗策略进展:揭示tubuloside A靶向分选酶A及减轻致病性的效力
World J Microbiol Biotechnol. 2025 Jan 10;41(2):29. doi: 10.1007/s11274-024-04185-7.
3
Proline, a unique amino acid whose polymer, polyproline II helix, and its analogues are involved in many biological processes: a review.
脯氨酸,一种独特的氨基酸,其聚合物、聚脯氨酸 II 螺旋及其类似物参与许多生物过程:综述。
Amino Acids. 2024 Aug 25;56(1):50. doi: 10.1007/s00726-024-03410-9.
4
Integrins as a bridge between bacteria and cells: key targets for therapeutic wound healing.整合素作为细菌与细胞之间的桥梁:治疗伤口愈合的关键靶点。
Burns Trauma. 2024 Jul 16;12:tkae022. doi: 10.1093/burnst/tkae022. eCollection 2024.
5
Levofloxacin prophylaxis in pediatric oncology and hematopoietic stem cell transplantation: a literature review.左氧氟沙星预防儿科肿瘤和造血干细胞移植:文献综述。
Pediatr Hematol Oncol. 2024 Sep;41(6):432-448. doi: 10.1080/08880018.2024.2353888. Epub 2024 Jul 8.
6
The wound microbiota: microbial mechanisms of impaired wound healing and infection.伤口菌群:影响伤口愈合和感染的微生物机制。
Nat Rev Microbiol. 2024 Aug;22(8):507-521. doi: 10.1038/s41579-024-01035-z. Epub 2024 Apr 4.
7
Evaluation of novel compounds as anti-bacterial or anti-virulence agents.评估新型化合物作为抗菌或抗毒剂的效果。
Front Cell Infect Microbiol. 2024 Mar 6;14:1370062. doi: 10.3389/fcimb.2024.1370062. eCollection 2024.
8
Integrins regulation of wound healing processes: insights for chronic skin wound therapeutics.整合素对伤口愈合过程的调控:慢性皮肤伤口治疗的新视角。
Front Cell Infect Microbiol. 2024 Mar 5;14:1324441. doi: 10.3389/fcimb.2024.1324441. eCollection 2024.
9
The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections.人细胞外基质蛋白在金黄色葡萄球菌生物膜感染中的作用。
FEMS Microbiol Rev. 2024 Jan 12;48(1). doi: 10.1093/femsre/fuae002.
10
Partnering essential oils with antibiotics: proven therapies against bovine mastitis.将精油与抗生素结合:针对奶牛乳腺炎的经过验证的治疗方法。
Front Cell Infect Microbiol. 2023 Sep 15;13:1265027. doi: 10.3389/fcimb.2023.1265027. eCollection 2023.