酒精性肝损伤的生化与临床方面
[Biochemical and clinical aspects of alcoholic liver damage].
作者信息
Eisenburg J
出版信息
Naturwissenschaften. 1976 Dec;63(12):556-69. doi: 10.1007/BF00622789.
PMID:1004621
Abstract
Alcoholism is the most common form of drug abuse and alcoholic liver disease is a major health problem which in terms of increasing incidence is only rivaled by viral hepatitis. Cirrhosis of the liver, most of which is probably alcoholic, is among the leading causes of morbidity and mortality between the ages of 25 to 65 in Western countries. Alcoholic liver disease includes adaptive and toxic ultrastructural alterations, alcoholic fatty liver, alcoholic hepatitis and alcoholic cirrhosis, later accompanied by hepatoma.
摘要
酒精中毒是药物滥用最常见的形式，酒精性肝病是一个主要的健康问题，就发病率不断上升而言，仅次于病毒性肝炎。肝硬化，其中大部分可能是酒精性的，是西方国家25至65岁人群发病和死亡的主要原因之一。酒精性肝病包括适应性和毒性超微结构改变、酒精性脂肪肝、酒精性肝炎和酒精性肝硬化，后期可并发肝癌。
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