• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

酒精性肝损伤的生化与临床方面

[Biochemical and clinical aspects of alcoholic liver damage].

作者信息

Eisenburg J

出版信息

Naturwissenschaften. 1976 Dec;63(12):556-69. doi: 10.1007/BF00622789.

DOI:10.1007/BF00622789
PMID:1004621
Abstract

Alcoholism is the most common form of drug abuse and alcoholic liver disease is a major health problem which in terms of increasing incidence is only rivaled by viral hepatitis. Cirrhosis of the liver, most of which is probably alcoholic, is among the leading causes of morbidity and mortality between the ages of 25 to 65 in Western countries. Alcoholic liver disease includes adaptive and toxic ultrastructural alterations, alcoholic fatty liver, alcoholic hepatitis and alcoholic cirrhosis, later accompanied by hepatoma.

摘要

酒精中毒是药物滥用最常见的形式,酒精性肝病是一个主要的健康问题,就发病率不断上升而言,仅次于病毒性肝炎。肝硬化,其中大部分可能是酒精性的,是西方国家25至65岁人群发病和死亡的主要原因之一。酒精性肝病包括适应性和毒性超微结构改变、酒精性脂肪肝、酒精性肝炎和酒精性肝硬化,后期可并发肝癌。

相似文献

1
[Biochemical and clinical aspects of alcoholic liver damage].酒精性肝损伤的生化与临床方面
Naturwissenschaften. 1976 Dec;63(12):556-69. doi: 10.1007/BF00622789.
2
[Alcoholic lesions of the liver (morphology and several questions concerning pathogenesis)].[肝脏酒精性病变(形态学及发病机制的若干问题)]
Arkh Patol. 1975;37(2):54-62.
3
[Alcoholic liver lesions].[酒精性肝损伤]
Med Klin. 1972 Nov 3;67(44):1419-24.
4
[Alcohol-induced liver diseases].[酒精性肝病]
Lakartidningen. 1974 May 29;71(22):2273-4.
5
Relation of alcoholic liver injury to cirrhosis.酒精性肝损伤与肝硬化的关系。
Clin Gastroenterol. 1975 May;4(2):247-72.
6
[Alcohol and liver damage].[酒精与肝脏损伤]
Dtsch Med Wochenschr. 1969 Jun 6;94(23):1213-7. doi: 10.1055/s-0028-1111195.
7
Alcoholic fatty liver: its pathogenesis and precursor role for hepatitis and cirrhosis.酒精性脂肪肝:其发病机制及在肝炎和肝硬化中的前驱作用。
Panminerva Med. 1976 Sep-Oct;18(9-10):346-58.
8
Hepatic and metabolic effects of alcohol (1966 to 1973).酒精的肝脏及代谢效应(1966年至1973年)
Gastroenterology. 1973 Nov;65(5):821-46.
9
Differences in hepatic and metabolic changes after acute and chronic alcohol consumption.急性和慢性饮酒后肝脏及代谢变化的差异。
Fed Proc. 1975 Oct;34(11):2060-74.
10
The spectrum of liver diseases in alcoholism.酒精中毒时肝脏疾病的谱
Aust N Z J Med. 1975 Feb;5(1):49-57. doi: 10.1111/j.1445-5994.1975.tb03255.x.

引用本文的文献

1
[Chemical mechanism of the effect of alcohol].[酒精作用的化学机制]
Naturwissenschaften. 1979 Jan;66(1):22-7. doi: 10.1007/BF00369351.

本文引用的文献

1
Crystalline alcohol dehydrogenase from horse liver.
Arch Biochem. 1948 Aug;18(2):361-3.
2
Properties of catalase. Catalysis of coupled oxidation of alcohols.过氧化氢酶的性质。醇类的偶联氧化催化作用。
Biochem J. 1945;39(4):293-301.
3
Metabolic alterations produced in the liver by chronic ethanol administration. Comparison between the effects produced by ethanol and by thyroid hormones.慢性乙醇给药对肝脏产生的代谢改变。乙醇和甲状腺激素产生的作用的比较。
Biochem J. 1973 Jun;134(2):523-9. doi: 10.1042/bj1340523.
4
Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity.慢性乙醇给药对肝脏产生的代谢改变。氧化能力增强。
Biochem J. 1973 Jun;134(2):507-14. doi: 10.1042/bj1340507.
5
Endogenous sthanol: a review.
Q J Stud Alcohol. 1961 Dec;22:554-74.
6
COLLAGEN AND CELL PROTEIN SYNTHESIS BY AN ESTABLISHED MAMMALIAN FIBROBLAST LINE.一种成熟的哺乳动物成纤维细胞系对胶原蛋白和细胞蛋白质的合成
Nature. 1964 Oct 24;204:347-9. doi: 10.1038/204347a0.
7
STUDIES ON THE PATHOGENESIS OF THE ETHANOL-INDUCED FATTY LIVER. II. EFFECT OF ETHANOL ON PALMITATE-1-C-14 METABOLISM BY THE ISOLATED PERFUSED RAT LIVER.乙醇诱导脂肪肝发病机制的研究。II. 乙醇对离体灌注大鼠肝脏棕榈酸-1-C-14代谢的影响。
J Clin Invest. 1964 Jul;43(7):1338-47. doi: 10.1172/JCI105009.
8
On the ternary complex of liver alcohol dehydrogenase with reduced coenzyme and isobutyramide. Effect of p-chloromercuriphenyl sulfonate and stability of the complex.
Arch Biochem Biophys. 1962 Dec;99:433-46. doi: 10.1016/0003-9861(62)90291-6.
9
[Fatty liver, its causes and concomitant diseases].
Dtsch Med Wochenschr. 1962 May 18;87:1049-55. doi: 10.1055/s-0028-1111865.
10
The intermediary metabolism of alcohol.
Am J Clin Nutr. 1961 Jul-Aug;9:426-31. doi: 10.1093/ajcn/9.4.426.