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[罗阿丝虫性眼病的外科蠕虫摘除术]

[Surgical worm extraction in loa loa ophthalmia].

作者信息

Sachs H G, Heep M, Gabel V P

机构信息

Universitäts Augenklinik Regensburg.

出版信息

Klin Monbl Augenheilkd. 1998 Dec;213(6):367-9. doi: 10.1055/s-2008-1035005.

Abstract

BACKGROUND

Loa Loa is a chronic parasitemic disease which is endemic in the tropical rain forests of Western Africa. Vector of this disease is a mangrove fly with the name Chrysops. Besides the eye worm and skin affections a systemic infection with microfilariae is common.

PATIENT

A West African tourist from Bangibe showed up at the university eye clinic. His complaints were a red eye and a mobile subconjunctival tumor (Fig. 1) that showed vermiform movements. The worm was transparent and 4-5 cm in length. After topical anaesthesia and the attempt to paralyze the worm (1) with Pilocarpine 2% it vanished. Two days later the patient showed up in the morning for the planned blood test. No worm was visible at that time but at noontime the blood test was carried out and at that time the worm was visible in the nasal conjunctiva. This time the worm was removed without delay under topical anaesthesia. The worm was fixed with a forceps through the conjunctiva which was opened for 0.5 cm. The worm was grasped with a second forceps and drawn out under massive vermiform movement. Systemic therapy was recommended with Hetrazan (Diethylcarbamazine) using Corticosteroides and Antihistamine to minimize allergic side effects by the therapy due to the systemic microfilariae blood load. Eosinophilia was 8%.

CONCLUSIONS

A subconjuctival Loa Loa worm can be removed under topical anaesthesia by fixing it with a forceps through the conjunctiva and opening it and grasping the worm with a second forceps. According to our experience the paralyzation with Pilocarpine cannot be realized. Careful systemic therapy avoiding reported allergic side effects with Hetrazan which is not available in Germany is necessary.

摘要

背景

罗阿丝虫病是一种慢性寄生虫病,在西非热带雨林地区流行。该病的传播媒介是一种名为螯蝇的红树林蝇。除了眼部蠕虫和皮肤病变外,微丝蚴的全身感染也很常见。

患者

一名来自班吉贝的西非游客来到大学眼科诊所。他的症状是眼睛发红和一个可移动的结膜下肿物(图1),肿物呈现蠕虫样蠕动。蠕虫呈透明状,长度为4 - 5厘米。在局部麻醉并用2%毛果芸香碱试图使蠕虫麻痹(1)后,它消失了。两天后,患者上午前来进行预定的血液检查。当时没有看到蠕虫,但中午进行血液检查时,蠕虫出现在鼻侧结膜。这次在局部麻醉下立即将蠕虫取出。通过切开0.5厘米的结膜,用镊子固定蠕虫。用另一把镊子抓住蠕虫,并在其剧烈蠕动时将其拉出。建议使用海群生(乙胺嗪)进行全身治疗,并使用皮质类固醇和抗组胺药,以尽量减少由于全身微丝蚴血症负荷导致的治疗引起的过敏副作用。嗜酸性粒细胞增多为8%。

结论

结膜下的罗阿丝虫可在局部麻醉下通过用镊子穿过结膜固定、切开结膜并用另一把镊子抓住蠕虫的方法取出。根据我们的经验,无法用毛果芸香碱实现麻痹。谨慎的全身治疗是必要的,要避免德国没有的海群生所报告的过敏副作用。

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