Theodossiadis G P, Ladas I D, Panagiotidis D N, Kollia A C, Voudouri A N, Theodossiadis P G
Department of Ophthalmology, Athens University School of Medicine, General Hospital of Athens, Greece.
Retina. 1999;19(1):6-11. doi: 10.1097/00006982-199901000-00002.
To investigate the pattern of congenital optic disk pits associated with maculopathy using indocyanine green angiography (ICG) and fluorescein angiography (FA).
Seventeen consecutive patients with unilateral congenital optic disk pit complicated by maculopathy were prospectively enrolled in the study. Complete ophthalmologic examination, color stereophotography, red-free photography, FA, and ICG angiography were performed on all patients during their first examination in our department.
Absolute hypofluorescence of the optic disk pit was noted in all eyes on ICG angiography. On the contrary, all eyes showed early hypofluorescence and late staining of the optic pit on FA. All 17 eyes presented a delineated late hyperfluorescence corresponding to the area of macular elevation on both ICG angiography and FA. The intensity of the hyperfluorescence was milder in cases with long-standing maculopathy.
Imaging of congenital optic disk pits associated or not with macular elevation using ICG angiography has not been reported in the literature. The increased hyperfluorescence in the late phases of the macular elevation in the studied eyes could be attributed to leakage of indocyanine or fluorescein dye into the schisis cavity and the subretinal fluid.
使用吲哚菁绿血管造影(ICG)和荧光素血管造影(FA)研究与黄斑病变相关的先天性视盘小凹的模式。
前瞻性纳入17例单侧先天性视盘小凹合并黄斑病变的连续患者。在所有患者于我科首次检查期间,对其进行了全面的眼科检查、彩色立体摄影、无赤光摄影、FA及ICG血管造影。
ICG血管造影显示所有患眼视盘小凹均为绝对低荧光。相反,所有患眼在FA上均表现为视盘小凹早期低荧光和晚期染色。17只患眼在ICG血管造影和FA上均呈现出与黄斑隆起区域相对应的界限清晰的晚期高荧光。在长期黄斑病变的病例中,高荧光强度较弱。
文献中尚未报道使用ICG血管造影对伴有或不伴有黄斑隆起的先天性视盘小凹进行成像。研究患眼中黄斑隆起晚期高荧光增强可能归因于吲哚菁绿或荧光素染料渗漏至视网膜劈裂腔和视网膜下液中。