Brown G C, Shields J A, Goldberg R E
Ophthalmology. 1980 Jan;87(1):51-65. doi: 10.1016/s0161-6420(80)35278-0.
The clinical characteristics of 75 eyes with congenital pits of the optic nerve head were reviewed, particularly in relation to associated serous retinal detachment. Retinal detachment was found in 52% of all eyes with pits and 63% of eyes with temporally located pits. Of 20 untreated eyes with a pit and coexistent macular retinal detachment followed for more than one year, 55% (11/20) had visual acuity less than or equal to 6/30 and 75% (15/20) had subretinal fluid at the most recent visit. Visual fields and intravenous fluorescein angiographic characteristics of pits are discussed and clinical evidence is presented supporting the theory that the associated subretinal fluid is derived from liquified vitreous.
回顾了75例视神经乳头先天性凹陷患者的临床特征，尤其涉及相关的浆液性视网膜脱离。在所有有凹陷的眼中，52%发生了视网膜脱离；在颞侧有凹陷的眼中，63%发生了视网膜脱离。对20例有凹陷且并存黄斑视网膜脱离、随访超过1年的未治疗患者进行观察，其中55%（11/20）的患者视力小于或等于6/30，75%（15/20）的患者在最近一次随访时存在视网膜下液。文中讨论了凹陷的视野及静脉荧光素血管造影特征，并提供了临床证据支持相关视网膜下液源自液化玻璃体的理论。
