安德森沙门氏菌噬菌体分型系统的分子调查。
Molecular survey of the Salmonella phage typing system of Anderson.
作者信息
Schmieger H
机构信息
Institute for Genetics and Microbiology, University of Munich, D-80638 Munich, Germany.
出版信息
J Bacteriol. 1999 Mar;181(5):1630-5. doi: 10.1128/JB.181.5.1630-1635.1999.
Abstract
Typing phages for Salmonella and the prophages of their typical propagation strains were analyzed at the DNA level. Most of them belong to the P22 branch of the lambdoid phages. Acquisition of new plating properties of the typing phages by propagation in particular strains can be due to different host specific modifications of the DNA or to recombination events with residing prophages which are reflected by changes in the respective DNA restriction patterns. It is concluded that the actually available set of typing phages is a historically unique combination of strains.
摘要
对沙门氏菌的分型噬菌体及其典型增殖菌株的原噬菌体进行了DNA水平分析。它们中的大多数属于λ样噬菌体的P22分支。分型噬菌体在特定菌株中增殖时获得新的平板培养特性，可能是由于DNA的不同宿主特异性修饰，或与驻留原噬菌体的重组事件，这通过各自DNA限制图谱的变化得以体现。得出的结论是，实际可用的分型噬菌体集合是菌株的一种历史上独特的组合。
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