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下一代胰管镜检查:经口电子胰管镜系统的研发

Pancreatoscopy for the next generation: development of the peroral electronic pancreatoscope system.

作者信息

Kodama T, Sato H, Horii Y, Tatsumi Y, Uehira H, Imamura Y, Kato K, Koshitani T, Yamane Y, Kashima K

机构信息

Third Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Gastrointest Endosc. 1999 Mar;49(3 Pt 1):366-71. doi: 10.1016/s0016-5107(99)70015-5.

DOI:10.1016/s0016-5107(99)70015-5
PMID:10049422
Abstract

BACKGROUND

To improve visualization of the pancreatic duct with a pancreatoscope, we have developed the smallest known electronic endoscope, that is, the peroral electronic pancreatoscope.

METHODS

This instrument (2.1 mm, external diameter) was developed with a 50k-pixel interline charge coupled device. A peroral fiberoptic pancreatoscope was used as control, connected to a video converter. The visibility of both systems was studied with a test chart. The model pancreatic duct, the oral mucosa, and the pancreatic ducts of a healthy control subject and patients with chronic pancreatitis were examined with both systems.

RESULTS

The smallest visible interval (with a 5 mm distance between the object and the distal end of the endoscope) was 0.07 mm with the peroral electronic pancreatoscope and 0.2 mm with the peroral fiberoptic pancreatoscope. The electronic instrument produced better images of the model pancreatic duct than the fiberoptic endoscope. A clear image of the small vessels of the oral mucosa was obtained with the electronic but not with the fiberoptic instrument. The fine vessel network of the pancreatic duct was visualized only with the electronic instrument; pancreatic duct stones and rough-surfaced pancreatic duct were shown more precisely with the electronic endoscope.

CONCLUSIONS

The peroral electronic pancreatoscope provides images of the fine detail of the pancreatic duct and will contribute to the diagnosis of pancreatic diseases.

摘要

背景

为了通过胰管镜更好地观察胰管,我们研发了已知最小的电子内窥镜,即经口电子胰管镜。

方法

该仪器(外径2.1毫米)采用50k像素隔行电荷耦合器件开发。将经口纤维胰管镜作为对照,连接到视频转换器。用测试图研究了两个系统的可视性。用这两个系统检查了模型胰管、口腔黏膜以及健康对照者和慢性胰腺炎患者的胰管。

结果

经口电子胰管镜的最小可视间隔(物体与内窥镜远端距离为5毫米时)为0.07毫米,经口纤维胰管镜为0.2毫米。电子仪器对模型胰管的成像比纤维内窥镜更好。电子仪器能获得口腔黏膜小血管的清晰图像,而纤维仪器则不能。只有电子仪器能观察到胰管的微血管网络;电子内窥镜能更精确地显示胰管结石和表面粗糙的胰管。

结论

经口电子胰管镜能提供胰管精细细节的图像,将有助于胰腺疾病的诊断。

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