Kanamaru Y, Etoh M, Song X G, Mikogami T, Hayasawa H, Ebina T, Minamoto N
Department of Food Science, Faculty of Agriculture, Gifu University, Japan.
Biosci Biotechnol Biochem. 1999 Jan;63(1):246-9. doi: 10.1271/bbb.63.246.
Rotavirus is the major cause of infectious diarrhea in infants and young children all over the world. We have found that a high-M(r) glycoprotein fraction from cow's milk is potent in inhibiting replication of human rotaviruses in vitro. Since the activity seems to be unique and specific, this fraction may be useful as a novel agent for treatment or prevention of rotavirus diarrhea.