Gupta R, Goyle A, Kashyap S, Agarwal M, Consul R, Jain B K
Department of Medicine, Monilek Hospital & Research Centre, Jawahar Nagar, Jaipur.
Indian Heart J. 1998 Sep-Oct;50(5):511-5.
The emerging epidemic of atherosclerotic cardiovascular diseases in developing countries may have its roots in childhood. We studied atherosclerosis risk factors--tobacco use, obesity, hypertension, total cholesterol level and dietary intake of atherogenic nutrients in adolescent school children aged 13-17 years in Western India. Two hundred thirty-seven children (89 boys, 148 girls) were examined and prevalence of risk factors determined. Family history of coronary heart disease was found in 16 (6.8%), smoking or tobacco use in one (0.4%) and obesity (BMI > 90th percentile) in 24 (10.1%), borderline hypertension (> or = 136/86) in 65 (27.4%) and definite hypertension (> or = 142/92) in 17 (7.2%). Borderline hypercholesterolaemia (170-199 mg/dL) was in 78 (32.9%) and definite hypercholesterolaemia (> or = 200 mg/dL) in 16 (6.8%). Mean calorie intake was 1450 +/- 348 per day. Fats provided 38.4 +/- 8 percent of the calories, saturated fats contributed to 20.3 +/- 6.4 percent of calories, monounsaturated fats to 12.9 +/- 2.4 percent and polyunsaturated fats to 5.0 +/- 3.7 percent. Dietary cholesterol intake was 164 +/- 95 mg/day, sodium chloride intake 12.8 +/- 5.7 gm/day and fibre intake 6.5 +/- 4.6 gm/day. This study shows a high prevalence of metabolic and dietetic coronary risk factors among adolescents of the middle- and upper-middle class in India.
发展中国家动脉粥样硬化性心血管疾病的流行趋势可能始于儿童时期。我们对印度西部13 - 17岁的青少年在校学生的动脉粥样硬化风险因素进行了研究,这些因素包括烟草使用、肥胖、高血压、总胆固醇水平以及致动脉粥样硬化营养物质的饮食摄入情况。对237名儿童(89名男孩,148名女孩)进行了检查,并确定了风险因素的患病率。发现有16人(6.8%)有冠心病家族史,1人(0.4%)吸烟或使用烟草,24人(10.1%)肥胖(体重指数>第90百分位数),65人(27.4%)为临界高血压(≥136/86),17人(7.2%)为确诊高血压(≥142/92)。78人(32.9%)为临界高胆固醇血症(170 - 199毫克/分升),16人(6.8%)为确诊高胆固醇血症(≥200毫克/分升)。平均每日热量摄入为1450±348千卡。脂肪提供了38.4±8%的热量,饱和脂肪占热量的20.3±6.4%,单不饱和脂肪占12.9±2.4%,多不饱和脂肪占5.0±3.7%。膳食胆固醇摄入量为164±95毫克/天,氯化钠摄入量为12.8±5.7克/天,纤维摄入量为6.5±4.6克/天。这项研究表明,印度中上层阶级青少年中代谢和饮食性冠心病风险因素的患病率很高。