Matioli G T
USC Medical School, Los Angeles, CA 90033, USA.
Med Hypotheses. 1998 Dec;51(6):485-8. doi: 10.1016/s0306-9877(98)90069-x.
The paper discusses a mechanism for short-long duplications of segments of somatic chromatids in cancer cells. Based on the Frenkel-Kontorova model, the mechanism accounts for the high incidence of duplications on the long arm of almost all chromatids.
本文讨论了癌细胞中体细胞染色单体片段长短重复的一种机制。基于弗伦克尔-康托洛娃模型,该机制解释了几乎所有染色单体长臂上重复发生率高的原因。