Fehlinger R, Schulz A, Ubelhack R, Vesper J
Psychiatr Neurol Med Psychol (Leipz). 1976 Aug;28(8):458-65.
An analysis of the types of attacks occurring in tetanus patients shows that epileptic attacks are a relatively frequent occurrence in such patients. In patients under anti-epileptic therapy it is readily possible for the clinical picture to be concealed, and this may then result in irreversible damage due to the disturbance of metabolism remaining uninfluenced. It is recommended that the treatment of patients with cerebral attacks should include measures aimed at preventing the occurrence in them of convulsions resulting from the particular metabolic situation in the case of tetanus. What is also pointed out by the authors in their present paper is that tetanus patients treated with anticonvulsives and particularly disposed sufferers from epilepsy may show a deterioration of the metabolic situation and a loss of stability of the vitamin D metabolism, respectively. Accordingly, it is advisable that regular clinical and paraclinical checks be made in the case of the two syndromes referred to above.
对破伤风患者所发生的发作类型进行分析表明,癫痫发作在这类患者中较为常见。对于接受抗癫痫治疗的患者,临床症状很容易被掩盖,进而可能因代谢紊乱未得到干预而导致不可逆转的损害。建议对脑部发作患者的治疗应包括采取措施,以防止因破伤风患者特殊的代谢状况而引发惊厥。作者在其论文中还指出,接受抗惊厥药物治疗的破伤风患者,尤其是癫痫易感患者,可能分别出现代谢状况恶化和维生素D代谢稳定性丧失的情况。因此,对于上述两种综合征患者,建议定期进行临床和辅助检查。