Fueki R, Kleisbauer J P, Feliciano J M, Poirier R, Cohen G, Laval P
Respiration. 1976;33(6):425-35. doi: 10.1159/000193760.
Study of the influence of some parameters upon flow-volume curves and pressure-type body plethysmography during inhalation tests (acetylcholine; metaproterenol) in 10 asthmatic patients (5 males and 5 females). Although the specific conductance decreased when bronchoconstriction was induced and returned to values superior to those measured before provocation when a bronchodilator was administered, changes in specific conductance did not always parallel those of flow-volume curves (V/V), maximum expiratory volume/sec (VEMS) and mid-miximum expiratory flow rate (MMEFR). All the parameters of V/V used here are well correlated with VEMS and MMEFR but not so with the specific conductance. The inverse correlation between the time constants of V/V and residual/total pulmonary capacity (VR/CT) before provocation and the significant decrease after provocation, indicate that V 60 (or 70%) CT and V 75% vital capacity (CV) are most valuable for the evaluation of physiopathological ventilatory changes occurring in bronchoconstriction.
对10名哮喘患者（5名男性和5名女性）在吸入测试（乙酰胆碱；间羟异丙肾上腺素）期间某些参数对流量-容积曲线和压力型体容积描记法的影响进行研究。尽管诱导支气管收缩时比电导降低，而给予支气管扩张剂后比电导恢复到高于激发前测量值的水平，但比电导的变化并不总是与流量-容积曲线（V/V）、最大呼气量/秒（VEMS）和最大呼气中期流速（MMEFR）的变化平行。这里使用的所有V/V参数与VEMS和MMEFR都有很好的相关性，但与比电导的相关性则不然。激发前V/V的时间常数与残气量/肺总量（VR/CT）之间的负相关以及激发后的显著下降表明，V 60（或70%）CT和V 75%肺活量（CV）对于评估支气管收缩时发生的生理病理通气变化最有价值。
