Planiol T, Guillemart A, Besnard J C, Groussin P
Rev Neurol (Paris). 1976 Nov;132(11):779-90.
A total of 122 cases of various neurological diagnoses (among which 72 cerebral infarcts, 7 intracerebral hematomas and 38 intracranial tumors) had two separate brain scans, performed within 48 hours of each other after the administration of pertechnetate and technetium stannous pyrophosphate. The comparison of the resulting seans indicates that, in addition of an osseous accumulation, the pyrophosphate localizes greatly in ischemic cerebral lesions, especially those observed during the second week of evolution. It seems that the uptake of pyrophosphate reflects the area of anaerobic changes whereas the accumulation of pertechnetate depends on the disruption of the blood brain barrier. The scintigraphic diagnostic of cerebral infarctions is greatly improved.
总共122例各种神经疾病诊断病例(其中72例脑梗死、7例脑内血肿和38例颅内肿瘤)在注射高锝酸盐和焦磷酸亚锡锝后48小时内进行了两次独立的脑部扫描。对所得扫描结果的比较表明,除了骨累积外,焦磷酸盐在缺血性脑病变中大量定位,尤其是在病程第二周观察到的病变。似乎焦磷酸盐的摄取反映了无氧变化的区域,而高锝酸盐的累积则取决于血脑屏障的破坏。脑梗死的闪烁扫描诊断有了很大改善。