Iannelli A, Meglio M
Riv Neurol. 1976 Mar-Apr;46(2):116-29.
A comparative study of the antiepileptic action of Clonazepam, phenythoin-natrium and phenobarbital has been performed in acute experiments in rabbits. The effort of the three drugs, administered intravenously, was studied on a) the epileptic activity induced by electrical stimulation of the amygdala, b) the interictal and c) ictal epileptic activity of an amygdaloid chemical focus (penicillin in gel). Clonazepam has a definite higher capacity, than the other drugs examined to prevent or to reduce the phenomenon of generalization of epilepsy. However, its effect has a shorter duration.
在兔的急性实验中对氯硝西泮、苯妥英钠和苯巴比妥的抗癫痫作用进行了比较研究。研究了静脉注射这三种药物对以下方面的作用：a) 电刺激杏仁核诱发的癫痫活动；b) 发作间期；c) 杏仁核化学性病灶（凝胶中的青霉素）的发作期癫痫活动。与所研究的其他药物相比，氯硝西泮在预防或减轻癫痫泛化现象方面具有明显更高的能力。然而，其作用持续时间较短。
