Robson J M, Harte G J, Osborne D R, McCormack J G
Sullivan Nicolaides Pathology, Taringa, Australia.
Clin Infect Dis. 1999 Feb;28(2):274-8. doi: 10.1086/515102.
The case of a 9-year-old girl with cat-scratch disease (CSD) complicated by development of a paravertebral mass and osteomyelitis is presented. Following multiple scratches and inguinal lymphadenopathy, she developed back pain, and imaging demonstrated a paravertebral mass with evidence of osteomyelitis involving vertebra T9. The diagnosis was made on the basis of detection of Bartonella henselae by use of molecular techniques on an aspirate from the vertebral column and supportive serology for infection with B. henselae. Eleven other cases of this unusual manifestation associated with CSD have been reported in the literature and are reviewed. The patient was treated with gentamicin, followed by rifampicin and trimethoprim-sulfamethoxazole, orally and made a favorable recovery over 7 months. This is comparable with other case reports, regardless of the choice of antibiotic therapy. CSD in immunocompetent hosts is not always self-limiting, and tissues beyond the lymph nodes can be involved.
本文报告了一例9岁女童患猫抓病(CSD)并伴有椎旁肿块和骨髓炎的病例。在多次抓伤和腹股沟淋巴结病后,她出现背痛,影像学检查显示有一个椎旁肿块,并有累及T9椎体的骨髓炎迹象。通过对脊柱吸出物采用分子技术检测汉赛巴尔通体,并结合支持性血清学检查发现感染汉赛巴尔通体,从而做出诊断。文献中还报道并回顾了另外11例与CSD相关的这种不寻常表现的病例。患者先接受庆大霉素治疗,随后口服利福平及甲氧苄啶-磺胺甲恶唑,7个月后康复良好。无论选择何种抗生素治疗,这与其他病例报告的情况相当。免疫功能正常宿主的CSD并非总是自限性的,且可累及淋巴结以外的组织。