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[Adverse drug reactions in the Spanish medical bibliographic literature: a comparison of 3 periods].

作者信息

López-Oliva A G, Vargas Castrillón E, García Mateos M, García Arenillas M, Terleira Fernández A, Moreno González A

机构信息

Unidad de Uso Racional de Medicamentos, Area 1 de Atención Primaria, Madrid.

出版信息

Med Clin (Barc). 1999 Jan 23;112(2):55-6.

PMID:10065430
Abstract

BACKGROUND

A quantitative and qualitative assessment of reports on suspected adverse drug reactions (ARD) in Spanish medical literature was carried out.

MATERIALS AND METHODS

The periods analysed were 1972-1974, 1986-1988 and 1992-1994, and the medical journals were Anales de Medicina Interna, Medicina Clínica and Revista Clínica Española. We selected all articles including specific information on suspect ADR.

RESULTS

The percentage of articles has increased considerably (1972-1974: 2.1%, 1986-1988: 5.7%, and 1992-1994: 8.2%). In spite of this growth, the qualitative data studied have not significantly improved.

CONCLUSIONS

It is necessary to device some mechanism in order to improve ADR reporting.

摘要

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