Riou-Khamlichi C, Huntley R, Jacqmard A, Murray J A
Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, UK.
Science. 1999 Mar 5;283(5407):1541-4. doi: 10.1126/science.283.5407.1541.
Cytokinins are plant hormones that regulate plant cell division. The D-type cyclin CycD3 was found to be elevated in a mutant of Arabidopsis with a high level of cytokinin and to be rapidly induced by cytokinin application in both cell cultures and whole plants. Constitutive expression of CycD3 in transgenic plants allowed induction and maintenance of cell division in the absence of exogenous cytokinin. Results suggest that cytokinin activates Arabidopsis cell division through induction of CycD3 at the G1-S cell cycle phase transition.
细胞分裂素是调节植物细胞分裂的植物激素。在拟南芥的一个细胞分裂素水平较高的突变体中，发现D型细胞周期蛋白CycD3水平升高，并且在细胞培养物和整株植物中，细胞分裂素处理均可快速诱导其表达。在转基因植物中组成型表达CycD3可在无外源细胞分裂素的情况下诱导并维持细胞分裂。结果表明，细胞分裂素通过在G1-S细胞周期阶段转变时诱导CycD3来激活拟南芥的细胞分裂。
