专性细胞内寄生虫的多样栖息地。
The diverse habitats of obligate intracellular parasites.
作者信息
Hackstadt T
机构信息
Host-Parasite Interactions Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA.
出版信息
Curr Opin Microbiol. 1998 Feb;1(1):82-7. doi: 10.1016/s1369-5274(98)80146-x.
Bacterial obligate intracellular parasites have evolved diverse mechanisms for evasion of host cellular defenses. These mechanisms involve adaptations for survival in distinct intracellular compartments. Intracellular niches inhabited by obligate intracellular parasites include the cytoplasm, arrested early endosomes, lysosomes, and vesicles that do not fuse with the endosomal compartment but intersect with an exocytic pathway.
细菌专性胞内寄生物已经进化出多种逃避宿主细胞防御的机制。这些机制涉及在不同细胞内区室中生存的适应性变化。专性胞内寄生物所占据的细胞内生态位包括细胞质、停滞的早期内体、溶酶体以及不与内体区室融合但与外排途径相交的囊泡。
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