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Immunological features of Pneumocystis carinii infection in humans.卡氏肺孢子虫感染在人类中的免疫学特征。
Clin Diagn Lab Immunol. 1999 Mar;6(2):149-55. doi: 10.1128/CDLI.6.2.149-155.1999.
2
Western blot analysis of rat Pneumocystis carinii antigens using convalescent rat sera and rabbit anti-gp120.使用恢复期大鼠血清和兔抗gp120对大鼠卡氏肺孢子虫抗原进行蛋白质印迹分析。
J Eukaryot Microbiol. 1996 Sep-Oct;43(5):30S. doi: 10.1111/j.1550-7408.1996.tb04967.x.
3
Recognition of Pneumocystis carinii antigens by local antibody-secreting cells following resolution of P. carinii pneumonia in mice.小鼠卡氏肺孢子虫肺炎消退后，局部抗体分泌细胞对卡氏肺孢子虫抗原的识别
J Infect Dis. 1998 Jul;178(1):235-42. doi: 10.1086/515607.
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Immunization with recombinant Pneumocystis carinii p55 antigen provides partial protection against infection: characterization of epitope recognition associated with immunization.用重组卡氏肺孢子虫p55抗原免疫可提供部分抗感染保护：与免疫相关的表位识别特征
Microbes Infect. 2000 Feb;2(2):127-36. doi: 10.1016/s1286-4579(00)00275-6.
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Pneumocystis carinii organisms obtained from rats, ferrets, and mice are antigenically different.从大鼠、雪貂和小鼠身上获取的卡氏肺孢子虫生物体在抗原性上有所不同。
Infect Immun. 1993 Apr;61(4):1315-9. doi: 10.1128/iai.61.4.1315-1319.1993.
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Antibody response to a major human Pneumocystis carinii surface antigen in patients without evidence of immunosuppression and in patients with suspected atypical pneumonia.对无免疫抑制证据患者及疑似非典型肺炎患者体内针对一种主要人卡氏肺孢子虫表面抗原的抗体反应。
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Immunization with Pneumocystis Cross-Reactive Antigen 1 (Pca1) Protects Mice against Pneumocystis Pneumonia and Generates Antibody to Pneumocystis jirovecii.用肺孢子菌交叉反应抗原1（Pca1）免疫可保护小鼠免受肺孢子菌肺炎感染，并产生针对耶氏肺孢子菌的抗体。
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Characterization of major surface glycoprotein genes of human Pneumocystis carinii and high-level expression of a conserved region.人卡氏肺孢子虫主要表面糖蛋白基因的特性及一个保守区域的高水平表达
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Pneumocystis carinii from pigs and humans are antigenically distinct.来自猪和人类的卡氏肺孢子虫在抗原性上是不同的。
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Serologic responses to Pneumocystis carinii antigens in health and disease.健康与疾病状态下对卡氏肺孢子虫抗原的血清学反应。
J Infect Dis. 1990 Feb;161(2):296-306. doi: 10.1093/infdis/161.2.296.

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Pneumonia: A Review of Management in Human Immunodeficiency Virus (HIV) and Non-HIV Immunocompromised Patients.肺炎：人类免疫缺陷病毒（HIV）及非HIV免疫功能低下患者的管理综述
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Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase.固有短尾素耐药性在毛霉菌中是由于羊毛固醇 14α-去甲基酶的一个进化保守的氨基酸取代引起的。
Sci Rep. 2017 Nov 21;7(1):15898. doi: 10.1038/s41598-017-16123-9.
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Humoral immune responses to Pneumocystis jirovecii antigens in HIV-infected and uninfected young children with pneumocystis pneumonia.感染和未感染人类免疫缺陷病毒的患肺孢子菌肺炎幼儿对耶氏肺孢子菌抗原的体液免疫反应
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Serologic responses to recombinant Pneumocystis jirovecii major surface glycoprotein among Ugandan patients with respiratory symptoms.乌干达呼吸道症状患者对重组肺孢子菌主要表面糖蛋白的血清学反应。
PLoS One. 2012;7(12):e51545. doi: 10.1371/journal.pone.0051545. Epub 2012 Dec 21.
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Serum antibody levels to the Pneumocystis jirovecii major surface glycoprotein in the diagnosis of P. jirovecii pneumonia in HIV+ patients.血清抗体水平对卡氏肺孢子虫主要表面糖蛋白在 HIV+ 患者卡氏肺孢子虫肺炎的诊断。
PLoS One. 2010 Dec 9;5(12):e14259. doi: 10.1371/journal.pone.0014259.
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Seroepidemiological study of Pneumocystis jirovecii infection in healthy infants in Chile using recombinant fragments of the P. jirovecii major surface glycoprotein.采用重组的肺孢子菌主要表面糖蛋白片段对智利健康婴儿肺孢子菌感染的血清流行病学研究。
Int J Infect Dis. 2010 Dec;14(12):e1060-6. doi: 10.1016/j.ijid.2010.07.003.
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Evidence for high prevalence of Pneumocystis jirovecii exposure among Cameroonians.喀麦隆人感染耶氏肺孢子菌的高流行率证据。
Acta Trop. 2009 Nov;112(2):219-24. doi: 10.1016/j.actatropica.2009.07.030. Epub 2009 Aug 7.
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Geographical variation in serological responses to recombinant Pneumocystis jirovecii major surface glycoprotein antigens.针对重组耶氏肺孢子菌主要表面糖蛋白抗原的血清学反应的地理差异。
Clin Microbiol Infect. 2009 Oct;15(10):937-42. doi: 10.1111/j.1469-0691.2009.02716.x. Epub 2009 Mar 21.
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Pneumocystis colonization in immunocompetent and simian immunodeficiency virus-infected cynomolgus macaques.免疫功能正常和感染猿猴免疫缺陷病毒的食蟹猴中的肺孢子菌定植
J Infect Dis. 2009 Jan 1;199(1):89-96. doi: 10.1086/595297.

本文引用的文献

1
On the function of repetitive domains in protein antigens of Plasmodium and other eukaryotic parasites.疟原虫及其他真核寄生虫蛋白质抗原中重复结构域的功能
Parasitol Today. 1991 May;7(5):99-105. doi: 10.1016/0169-4758(91)90166-l.
2
Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation.感染HIV-1的人肺泡巨噬细胞对卡氏肺孢子虫的结合和吞噬作用降低，这与甘露糖受体下调有关。
J Clin Invest. 1998 Oct 1;102(7):1332-44. doi: 10.1172/JCI560.
3
Characterization of major surface glycoprotein genes of human Pneumocystis carinii and high-level expression of a conserved region.人卡氏肺孢子虫主要表面糖蛋白基因的特性及一个保守区域的高水平表达
Infect Immun. 1998 Sep;66(9):4268-73. doi: 10.1128/IAI.66.9.4268-4273.1998.
4
Immunization with the major surface glycoprotein of Pneumocystis carinii elicits a protective response.用卡氏肺孢子虫主要表面糖蛋白进行免疫可引发保护性反应。
Vaccine. 1998 Jul;16(11-12):1149-57. doi: 10.1016/s0264-410x(98)80113-8.
5
Recognition of Pneumocystis carinii antigens by local antibody-secreting cells following resolution of P. carinii pneumonia in mice.小鼠卡氏肺孢子虫肺炎消退后，局部抗体分泌细胞对卡氏肺孢子虫抗原的识别
J Infect Dis. 1998 Jul;178(1):235-42. doi: 10.1086/515607.
6
Susceptibility to Pneumocystis carinii in mice is dependent on simultaneous deletion of IFN-gamma and type 1 and 2 TNF receptor genes.小鼠对卡氏肺孢子虫的易感性取决于同时缺失干扰素-γ以及1型和2型肿瘤坏死因子受体基因。
J Immunol. 1998 Jul 1;161(1):360-6.
7
Immunization with Pneumocystis carinii gpA is immunogenic but not protective in a mouse model of P. carinii pneumonia.用卡氏肺孢子虫糖蛋白A进行免疫接种在卡氏肺孢子虫肺炎小鼠模型中具有免疫原性，但无保护作用。
Infect Immun. 1998 Jul;66(7):3179-82. doi: 10.1128/IAI.66.7.3179-3182.1998.
8
Activation and suppression of natural cellular immune functions by Pneumocystis carinii.卡氏肺孢子菌对天然细胞免疫功能的激活与抑制
Immunobiology. 1998 Feb;198(4):343-60. doi: 10.1016/S0171-2985(98)80044-2.
9
Adoptive transfer of specific lymphocyte populations sensitized to the major surface glycoprotein of Pneumocystis carinii decreases organism burden while increasing survival rate in the rat.将对卡氏肺孢子虫主要表面糖蛋白致敏的特定淋巴细胞群体进行过继转移，可降低大鼠体内的病原体负荷，同时提高其存活率。
J Eukaryot Microbiol. 1997 Nov-Dec;44(6):23S-24S. doi: 10.1111/j.1550-7408.1997.tb05750.x.
10
CD4 lymphocyte counts and mortality in AIDS patients requiring mechanical ventilator support due to Pneumocystis carinii pneumonia.因卡氏肺孢子虫肺炎需要机械通气支持的艾滋病患者的CD4淋巴细胞计数与死亡率
Chest. 1998 Feb;113(2):430-3. doi: 10.1378/chest.113.2.430.

Immunological features of Pneumocystis carinii infection in humans.

作者信息

Walzer P D

机构信息

Veterans Affairs Medical Center, Cincinnati, Ohio 45220, USA.

出版信息

Clin Diagn Lab Immunol. 1999 Mar;6(2):149-55. doi: 10.1128/CDLI.6.2.149-155.1999.

DOI:10.1128/CDLI.6.2.149-155.1999
PMID:10066645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC95678/
Abstract
摘要