Autio P, Kariniemi A L
Department of Dermatology, Helsinki University Central Hospital, Helsinki FIN 00250, Finland.
Eur J Dermatol. 1999 Mar;9(2):118-21.
Life-saving mastectomy and radiation therapy are established in the treatment of early stage breast cancer. Angiosarcoma, i.e. malignant angioendothelioma, is a rare tumor which can develop after several years of such treatment. The number of post-operative and post-irradiation angiosarcomas has increased in recent years. We report four cases of angiosarcoma which occurred after treatment of breast cancer and review the literature. In two of these cases the angiosarcoma developed on the irradiated breast skin after partial mastectomy and radiation therapy, in the other two cases the angiosarcoma appeared on a chronically edematous arm after radical mastectomy and radiation therapy.
挽救生命的乳房切除术和放射治疗是早期乳腺癌治疗的既定方法。血管肉瘤，即恶性血管内皮瘤，是一种罕见的肿瘤，可在这种治疗数年之后发生。近年来，术后和放疗后血管肉瘤的数量有所增加。我们报告了4例乳腺癌治疗后发生的血管肉瘤病例，并对文献进行了综述。其中2例血管肉瘤发生在保乳手术和放射治疗后受照射的乳房皮肤上，另外2例血管肉瘤出现在根治性乳房切除术和放射治疗后长期水肿的手臂上。
