Forssmann K, Singer M V
IV. Medizinische Universitätsklinik, Klinikum Mannheim, Universität Heidelberg.
Praxis (Bern 1994). 1999 Jan 7;88(1-2):13-7.
The standard treatment of acute pancreatitis is primarily supportive, including a well standardized conservative therapy and additionally specific interventions in complicated disease. The role of early endoscopic retrograde cholangiopancreatography in acute pancreatitis has been discussed for about 20 years. The etiology of pancreatitis plays an important role in making the decision for early interventional treatment. The results of clinical trials about early interventional treatment of acute biliary pancreatitis demonstrate that the outcome of patients without signs of biliary stone impaction or acute cholangitis is burdened by more severe complications than in patients treated conservatively. Urgent endoscopic retrograde cholangiopancreatography, endoscopic sphincterotomy and stone extraction within 72 hours of admission reduces the frequency of major complications only in patients with acute biliary pancreatitis with obstructive jaundice or biliary sepsis.
急性胰腺炎的标准治疗主要是支持性治疗,包括规范的保守治疗,以及对复杂病情的特定干预措施。早期内镜逆行胰胆管造影术在急性胰腺炎中的作用已被讨论了约20年。胰腺炎的病因在决定早期介入治疗中起着重要作用。关于急性胆源性胰腺炎早期介入治疗的临床试验结果表明,没有胆石嵌顿或急性胆管炎迹象的患者,其并发症比保守治疗的患者更为严重。入院72小时内进行紧急内镜逆行胰胆管造影术、内镜括约肌切开术和取石术,仅能降低伴有梗阻性黄疸或胆源性脓毒症的急性胆源性胰腺炎患者的严重并发症发生率。