热带脾肿大综合征中IgM的代谢
Metabolism of IgM in the tropical splenomegaly syndrome.
作者信息
Fakunle Y M, Greenwood B M
出版信息
Trans R Soc Trop Med Hyg. 1976;70(4):346-8. doi: 10.1016/0035-9203(76)90097-3.
PMID:1006767
Abstract
IgM metabolism was studied in five patients with the tropical splenomegaly syndrome and in five controls. The half-life and turnover time of I125 IgM was similar in the two groups. We conclude that the raised serum IgM levels found in patients with the tropical splenomegaly syndrome are not due to decreased IgM catabolism but are due to increased IgM production.
摘要
对五名热带脾肿大综合征患者和五名对照者的IgM代谢进行了研究。两组中I125 IgM的半衰期和周转时间相似。我们得出结论，热带脾肿大综合征患者血清IgM水平升高并非由于IgM分解代谢减少，而是由于IgM产生增加。
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