热带脾肿大综合征中肝脏淋巴细胞浸润的性质。
The nature of hepatic lymphocytic infiltrates in the tropical splenomegaly syndrome.
作者信息
Fakunle Y M, Greenwood B M
出版信息
Clin Exp Immunol. 1982 Jun;48(3):546-50.
Abstract
The lymphocytes infiltrating the liver of patients with tropical splenomegaly syndrome (TSS) were shown to be mainly T lymphocytes. Migration of leucocytes obtained from patients with TSS was inhibited by TSS liver extract, normal liver extract and liver-specific lipoprotein. These findings suggest that the hepatic infiltrates which occur in TSS are probably caused by a cell-mediated immune response to an antigen present in liver cells.
摘要
研究表明，热带脾肿大综合征（TSS）患者肝脏中的浸润淋巴细胞主要为T淋巴细胞。TSS肝提取物、正常肝提取物和肝脏特异性脂蛋白可抑制从TSS患者获取的白细胞迁移。这些发现提示，TSS中出现的肝脏浸润可能是由针对肝细胞中存在的一种抗原的细胞介导免疫反应所致。
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