Chantanakajornfung A, Naraporn N, Khumphai W, Bejavongkulchai M, Mitmoonpitak C, Wilde H
National Blood Center and Queen Saovabha Memorial, Institute of the Thai Red Cross Society, Bangkok.
Vaccine. 1999 Feb 26;17(7-8):979-81. doi: 10.1016/s0264-410x(98)00314-4.
This is a prospective post marketing study of 4496 patients presenting with severe animal bites in a canine rabies endemic region. They received human rabies immune globulin manufactured from volunteer blood donors at the National Blood Center of the Thai Red Cross Society at Bangkok. All patients also received a full course of tissue culture rabies vaccine. Only three subjects reported an adverse reaction (redness and itching at the immune globulin injection sites). None of the patients died during the subsequent 18 month follow up period.
这是一项针对犬类狂犬病流行地区4496例严重动物咬伤患者的前瞻性上市后研究。他们接受了由曼谷泰国红十字会国家血液中心的志愿献血者提供的人狂犬病免疫球蛋白。所有患者还接受了全程组织培养狂犬病疫苗。只有三名受试者报告了不良反应（免疫球蛋白注射部位发红和瘙痒）。在随后的18个月随访期内，没有患者死亡。
