• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

使用四极杆离子阱中的多级串联质谱（MSn）测定锌（II）-二乙烯三胺-二糖络合物中糖苷键的异头构型。

Determining anomericity of the glycosidic bond in Zn(II)-diethylenetriamine-disaccharide complexes using MSn in a quadrupole ion trap.

作者信息

Gaucher S P, Leary J A

机构信息

Department of Chemistry, University of California, Berkeley 94720, USA.

出版信息

J Am Soc Mass Spectrom. 1999 Mar;10(3):269-72. doi: 10.1016/S1044-0305(98)00149-4.

DOI:10.1016/S1044-0305(98)00149-4
PMID:10069047
Abstract

Zinc-diethylenetriamine (Zn-dien) N-glycoside complexes of four 1,4 and four 1,6 linked disaccharides are prepared. Each reaction mixture is ionized by electrospray and the resulting species [Zn(dien)(disaccharide)-H]+ is allowed to undergo collision-induced dissociation in a quadrupole ion trap. An MS3 analysis is used to differentiate alpha versus beta anomericity of the glycosidic bond in the disaccharide moiety. In addition, the MS2 and MS3 spectra can be used together to determine the linkage position of this glycosidic bond.

摘要

制备了四种1,4-连接和四种1,6-连接二糖的锌-二乙烯三胺（Zn-dien）N-糖苷配合物。每个反应混合物通过电喷雾进行离子化，然后使生成的物种[Zn(dien)(二糖)-H]+在四极离子阱中发生碰撞诱导解离。采用MS3分析来区分二糖部分中糖苷键的α型和β型异头物。此外，MS2和MS3光谱可一起用于确定该糖苷键的连接位置。

相似文献

1
Determining anomericity of the glycosidic bond in Zn(II)-diethylenetriamine-disaccharide complexes using MSn in a quadrupole ion trap.使用四极杆离子阱中的多级串联质谱（MSn）测定锌（II）-二乙烯三胺-二糖络合物中糖苷键的异头构型。
J Am Soc Mass Spectrom. 1999 Mar;10(3):269-72. doi: 10.1016/S1044-0305(98)00149-4.
2
Characterization of the glycosidic linkage of underivatized disaccharides by interaction with Pb(2+) ions.通过与Pb(2+)离子相互作用对未衍生化二糖的糖苷键进行表征。
J Mass Spectrom. 2007 Aug;42(8):999-1011. doi: 10.1002/jms.1220.
3
Stereochemical differentiation of mannose, glucose, galactose, and talose using zinc(II) diethylenetriamine and ESI-ion trap mass spectrometry.使用二乙烯三胺锌（II）和电喷雾离子阱质谱法对甘露糖、葡萄糖、半乳糖和塔罗糖进行立体化学鉴别。
Anal Chem. 1998 Jul 15;70(14):3009-14. doi: 10.1021/ac980023k.
4
Incremented alkyl derivatives enhance collision induced glycosidic bond cleavage in mass spectrometry of disaccharides.增加的烷基衍生物可增强二糖质谱分析中碰撞诱导的糖苷键裂解。
J Am Soc Mass Spectrom. 2003 Jan;14(1):63-78. doi: 10.1016/S1044-0305(02)00816-4.
5
Negative and positive ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and positive ion nano-electrospray ionization quadrupole ion trap mass spectrometry of peptidoglycan fragments isolated from various Bacillus species.从各种芽孢杆菌属物种中分离出的肽聚糖片段的负离子和正离子基质辅助激光解吸/电离飞行时间质谱以及正离子纳米电喷雾电离四极杆离子阱质谱。
J Mass Spectrom. 2001 Feb;36(2):124-39. doi: 10.1002/jms.109.
6
Distinguishing Linkage Position and Anomeric Configuration of Glucose-Glucose Disaccharides by Water Adduction to Lithiated Molecules.通过水加成到锂化分子来区分葡萄糖-葡萄糖二糖的连接位置和端基构型。
Anal Chem. 2018 Feb 6;90(3):2048-2054. doi: 10.1021/acs.analchem.7b04162. Epub 2018 Jan 16.
7
Determination of linkage position and anomeric configuration in Hex-Fuc disaccharides using electrospray ionization tandem mass spectrometry.使用电喷雾电离串联质谱法测定己糖-岩藻糖二糖中的连接位置和异头构型。
Rapid Commun Mass Spectrom. 2004;18(17):1947-55. doi: 10.1002/rcm.1573.
8
Low energy induced homolytic fragmentation of flavonol 3-O-glycosides by negative electrospray ionization tandem mass spectrometry.负离子电喷雾电离串联质谱法研究黄酮醇3-O-糖苷的低能诱导均裂碎片化
Rapid Commun Mass Spectrom. 2014 Feb 28;28(4):385-95. doi: 10.1002/rcm.6794.
9
Increased glycosidic bond stabilities in 4-C-hydroxymethyl linked disaccharides.4-C-羟甲基连接二糖糖苷键稳定性的增加。
Carbohydr Res. 2011 Nov 8;346(15):2394-400. doi: 10.1016/j.carres.2011.08.030. Epub 2011 Sep 2.
10
Reactions of palladium and gold complexes with zinc-thiolate chelates using electrospray mass spectrometry and X-ray diffraction: molecular identification of [Pd(bme-dach)], [Au(bme-dach]+ and [ZnCl(bme-dach)]2Pd.利用电喷雾质谱和 X 射线衍射研究钯和金配合物与锌-硫醇配合物的反应：[Pd(bme-dach)]、[Au(bme-dach)]+ 和 [ZnCl(bme-dach)]2Pd 的分子鉴定。
Dalton Trans. 2009 Dec 28(48):10896-903. doi: 10.1039/b917748p. Epub 2009 Nov 17.

引用本文的文献

1
A New Strategy Coupling Ion-Mobility-Selective CID and Cryogenic IR Spectroscopy to Identify Glycan Anomers.一种新策略，将离子淌度选择 CID 和低温红外光谱相结合，用于鉴定聚糖差向异构体。
J Am Soc Mass Spectrom. 2022 May 4;33(5):859-864. doi: 10.1021/jasms.2c00043. Epub 2022 Apr 19.
2
Assignment of the stereochemistry and anomeric configuration of sugars within oligosaccharides via overlapping disaccharide ladders using MS(n).通过使用MS(n) 的重叠二糖阶梯来确定寡糖中糖的立体化学和异头构型。
J Am Soc Mass Spectrom. 2014 Aug;25(8):1441-50. doi: 10.1007/s13361-014-0881-4. Epub 2014 Apr 11.
3
Structurally informative tandem mass spectrometry of highly sulfated natural and chemoenzymatically synthesized heparin and heparan sulfate glycosaminoglycans.

本文引用的文献

1
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of underivatized and permethylated gangliosides.未经衍生和全甲基化神经节苷脂的基质辅助激光解吸电离飞行时间质谱分析。
J Am Soc Mass Spectrom. 1992 Nov;3(8):785-96. doi: 10.1016/1044-0305(92)80001-2.
2
Differentiation of stereochemistry of glycosidic bond configuration: Tandem mass spectrometry of diastereomeric cobalt-glucosyl-glucose disaccharide complexes.糖键构型的立体化学区分：非对映异构钴-葡萄糖-葡萄糖二糖配合物的串联质谱。
J Am Soc Mass Spectrom. 1996 Sep;7(9):953-7. doi: 10.1016/1044-0305(96)80513-7.
3
High-energy collision-induced dissociation mass spectrometry of synthetic mannose-6-phosphate oligosaccharides.
高度硫酸化天然和化学酶合成肝素及硫酸乙酰肝素糖胺聚糖的结构信息串联质谱分析。
Mol Cell Proteomics. 2013 Apr;12(4):979-90. doi: 10.1074/mcp.M112.026880. Epub 2013 Feb 21.
4
Linkage and branch analysis of high-mannose oligosaccharides using closed-ring labeling of 8-aminopyrene-1,3,6-trisulfonate and p-aminobenzoic ethyl ester and negative ion trap mass spectrometry.利用 8-氨基芘-1,3,6-三磺酸和对氨基苯甲酸乙酯的闭环标记以及负离子阱质谱法对高甘露糖寡糖进行连锁和分支分析。
J Am Soc Mass Spectrom. 2012 Aug;23(8):1408-18. doi: 10.1007/s13361-012-0420-0. Epub 2012 Jun 7.
5
Separation of sodiated isobaric disaccharides and trisaccharides using electrospray ionization-atmospheric pressure ion mobility-time of flight mass spectrometry.使用电喷雾电离-大气压离子淌度-飞行时间质谱法分离钠化等压二糖和三糖。
J Am Soc Mass Spectrom. 2005 May;16(5):660-9. doi: 10.1016/j.jasms.2005.01.010.
6
Determination of the glycosylation site of flavonoid monoglucosides by metal complexation and tandem mass spectrometry.通过金属络合和串联质谱法测定黄酮类单糖苷的糖基化位点
J Am Soc Mass Spectrom. 2004 Sep;15(9):1287-99. doi: 10.1016/j.jasms.2004.06.003.
7
Gas phase reactivity of isomeric arylglycosides towards amines. A chemical ionization mass spectrometry and tandem mass spectrometry study.
J Am Soc Mass Spectrom. 2004 Feb;15(2):244-52. doi: 10.1016/j.jasms.2003.10.014.
8
Application of self-ionization for enhancing stereochemical and positional effects from arylglycosides under electron ionization conditions in an ion trap mass spectrometer.在离子阱质谱仪的电子电离条件下，自电离用于增强芳基糖苷的立体化学和位置效应的应用。
J Am Soc Mass Spectrom. 2003 Aug;14(8):851-61. doi: 10.1016/S1044-0305(03)00332-5.
9
Incremented alkyl derivatives enhance collision induced glycosidic bond cleavage in mass spectrometry of disaccharides.增加的烷基衍生物可增强二糖质谱分析中碰撞诱导的糖苷键裂解。
J Am Soc Mass Spectrom. 2003 Jan;14(1):63-78. doi: 10.1016/S1044-0305(02)00816-4.
10
Multiple-stage mass spectrometric analysis of complex oligosaccharide antibiotics (everninomicins) in a quadrupole ion trap.
J Am Soc Mass Spectrom. 2002 Nov;13(11):1313-21. doi: 10.1016/S1044-0305(02)00624-4.
高能碰撞诱导解离质谱法分析合成的甘露糖-6-磷酸寡糖。
J Am Soc Mass Spectrom. 1996 Feb;7(2):182-8. doi: 10.1016/1044-0305(95)00635-4.
4
Evidence for linkage position determination in cobalt coordinated pentasaccharides using ion trap mass spectrometry.利用离子阱质谱法确定钴配位五糖中连接位置的证据。
J Am Soc Mass Spectrom. 1998 Nov;9(11):1125-34. doi: 10.1016/S1044-0305(98)00096-8.
5
Stereochemical differentiation of mannose, glucose, galactose, and talose using zinc(II) diethylenetriamine and ESI-ion trap mass spectrometry.使用二乙烯三胺锌（II）和电喷雾离子阱质谱法对甘露糖、葡萄糖、半乳糖和塔罗糖进行立体化学鉴别。
Anal Chem. 1998 Jul 15;70(14):3009-14. doi: 10.1021/ac980023k.
6
Electrospray ionization and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry of permethylated oligosaccharides.全甲基化低聚糖的电喷雾电离和基质辅助激光解吸/电离傅里叶变换离子回旋共振质谱分析
Anal Chem. 1998 Mar 1;70(5):857-64. doi: 10.1021/ac970562+.
7
Characterization of oligosaccharide composition and structure by quadrupole ion trap mass spectrometry.通过四极杆离子阱质谱法对寡糖组成和结构进行表征。
Rapid Commun Mass Spectrom. 1997;11(14):1493-504. doi: 10.1002/(SICI)1097-0231(199709)11:14<1493::AID-RCM40>3.0.CO;2-1.
8
Rapid, sensitive structure analysis of oligosaccharides.寡糖的快速、灵敏结构分析
Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1629-33. doi: 10.1073/pnas.94.5.1629.
9
Biological roles of oligosaccharides: all of the theories are correct.寡糖的生物学作用：所有理论都是正确的。
Glycobiology. 1993 Apr;3(2):97-130. doi: 10.1093/glycob/3.2.97.
10
Differentiation of Ca(2+)- and Mg(2+)-coordinated branched trisaccharide isomers: an electrospray ionization and tandem mass spectrometry study.
Anal Chem. 1993 Oct 15;65(20):2805-11. doi: 10.1021/ac00068a017.