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Effect of Cassava on motor co-ordination and neurotransmitter level in the albino rat.

作者信息

Mathangi D C, Mohan V, Namasivayam A

机构信息

Department of Physiology, Dr ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, India.

出版信息

Food Chem Toxicol. 1999 Jan;37(1):57-60. doi: 10.1016/s0278-6915(98)00099-4.

DOI:10.1016/s0278-6915(98)00099-4
PMID:10069482
Abstract

The root of Cassava, a tropical plant, is consumed in the tropics and has been attributed as the cause for various tropical neuropathies. This study aims to discover the neurotoxic effects of chronic cassava consumption of Indian origin and the effect of malnutrition. The assessment is based on the motor co-ordination and brain neurotransmitters in rats. Cassava consumption reduced the motor co-ordination, but the changes in neurotransmitter levels due to cassava consumption (except for 5HT in corpus striatum) was identical with malnutrition-induced changes, indicating that the toxicity of chronic cassava consumption (of Indian origin) is mainly due to the associated protein calorie malnutrition (PCM).

摘要

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