Dodd D C, Marshall B E, Soma L R, Leatherman J
Vet Pathol. 1976;13(6):436-48. doi: 10.1177/030098587601300605.
Four anesthetized rabbits given intratracheal injections of hydrochloric acid, pH 1.5, 2 ml/kg, were killed 4 h later. A fifth rabbit was an untreated control. Each lung had a few red-brown patches of compression atelectasis. Microscopically, treated lungs had a severe exudative necrotizing bronchitis, bronchiolitis, and alveolitis. There was also intra-alveolar hemorrhage and edema. Electron microscopy showed folds, projections and focal swellings of type I cells lining affected alveoli. A morphometric study showed 69% of parenchyma to be normal, 26% edematous and 5% hemorrhagic. In the airways 58% of the epithelium was damaged.
给4只麻醉的兔子经气管注射pH值为1.5的盐酸，剂量为2毫升/千克，4小时后处死。第5只兔子作为未处理的对照。每只肺都有一些红棕色的压迫性肺不张斑片。显微镜下，经处理的肺出现严重的渗出性坏死性支气管炎、细支气管炎和肺泡炎。还存在肺泡内出血和水肿。电子显微镜显示，受影响肺泡的I型细胞有褶皱、突起和局灶性肿胀。一项形态计量学研究表明，69%的实质正常，26%水肿，5%出血。气道中58%的上皮受损。
