Vaduganathan P, He Z X, Vick G W, Mahmarian J J, Verani M S
Baylor College of Medicine and The Methodist Hospital, Houston, Texas, USA.
J Nucl Cardiol. 1999 Jan-Feb;6(1 Pt 1):3-10. doi: 10.1016/s1071-3581(99)90058-2.
Whether left ventricular function can be assessed accurately by gated single photon emission computed tomography (SPECT) in patients with myocardial infarction and severe perfusion defects is not well known.
Twenty-five patients with an acute myocardial infarction underwent 99mTc-labeled tetrofosmin (99mTc-tetrofosmin) gated SPECT and cine magnetic resonance imaging (MRI). Wall motion was assessed in 13 left ventricular segments using a 5-point scoring system ranging from 3 (normal) to -1 (dyskinetic). Exact agreement for wall motion scores between gated SPECT and MRI was excellent (92%, kappa = 0.82). Furthermore, correlations between the two techniques were also good for end-diastolic volume (r = 0.81, P < .0001), end-systolic volume (r = 0.92, P < .0001), and ejection fraction (r = 0.93, P < .0001).
In patients with a recent myocardial infarction, 99mTc-tetrofosmin gated SPECT provides reliable evaluation of global and regional ventricular function and volumes.
对于心肌梗死合并严重灌注缺损的患者，门控单光子发射计算机断层扫描（SPECT）能否准确评估左心室功能尚不清楚。
25例急性心肌梗死患者接受了99m锝标记的替曲膦（99mTc-替曲膦）门控SPECT和电影磁共振成像（MRI）检查。采用从3分（正常）到-1分（运动障碍）的5分评分系统对13个左心室节段的壁运动进行评估。门控SPECT和MRI之间壁运动评分的精确一致性非常好（92%，kappa = 0.82）。此外，两种技术之间舒张末期容积（r = 0.81，P <.0001）、收缩末期容积（r = 0.92，P <.0001）和射血分数（r = 0.93，P <.0001）的相关性也很好。
对于近期发生心肌梗死的患者，99mTc-替曲膦门控SPECT可对整体和局部心室功能及容积进行可靠评估。
