Chan J K
Department of Pathology, Queen Elizabeth Hospital, Hong Kong, S.A.R. China.
Mod Pathol. 1999 Feb;12(2):177-99.
Peripheral T-cell and NK-cell neoplasms account for only 10% of all non-Hodgkin's lymphomas, but they commonly pose great difficulties in diagnosis and classification. This article addresses the distinction between peripheral T-cell or NK-cell lymphoma and reactive lymphoid hyperplasia, the importance of recognition of the T-cell or NK-cell lineage for a lymphoma; and the importance of classification of a peripheral T- or NK-cell lymphoma. To solve these problems, it is imperative to adopt an integrated approach, taking the clinical features, morphologic findings, immunohistochemical profile, and/or genetic data into consideration.
外周T细胞和NK细胞肿瘤仅占所有非霍奇金淋巴瘤的10%，但它们在诊断和分类上通常存在很大困难。本文阐述了外周T细胞或NK细胞淋巴瘤与反应性淋巴组织增生之间的区别、识别淋巴瘤T细胞或NK细胞谱系的重要性，以及外周T细胞或NK细胞淋巴瘤分类的重要性。为解决这些问题，必须采用综合方法，将临床特征、形态学表现、免疫组化特征和/或遗传学数据考虑在内。
